产品名称
Anti-VLDL antibody produced in chicken, affinity isolated antibody, buffered aqueous solution
biological source
chicken
conjugate
unconjugated
antibody form
affinity isolated antibody
antibody product type
primary antibodies
clone
polyclonal
form
buffered aqueous solution
species reactivity
human
manufacturer/tradename
Genway 15-288-20090F
technique(s)
indirect ELISA: suitable
western blot: suitable
UniProt accession no.
shipped in
wet ice
storage temp.
−20°C
target post-translational modification
unmodified
Quality Level
Gene Information
human ... VLDLR(7436)
Application
Anti-VLDL antibody produced in chicken is suitable for indirect ELISA and western blotting analysis at a dilution of 1:500, for tissue or cell staining at a dilution of 1:200.
Biochem/physiol Actions
The very-low-density-lipoprotein receptor (VLDLR) is a transmembrane lipoprotein receptor and belongs to low-density-lipoprotein (LDL) receptor family. It is encoded by the VLDLR gene in humans. The LDL receptor gene family members are involved in ligand-mediated signal transduction. VLDLR is involved in the Reelin signaling pathway helping in neuronal migration in the cerebral cortex and cerebellum. It is strongly induced during adipogenesis and actively participates in adipocyte hypertrophy. VLDLR contributes to adipose tissue inflammation and mediates VLDL-induced lipid accumulation. It induces inflammation and ER stress in adipocytes and macrophages. VLDL receptor also plays a role in signaling processes.
Disclaimer
Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.
Physical form
Solution in phosphate buffered saline containing 0.02% sodium azide.
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存储类别
10 - Combustible liquids
wgk
WGK 1
flash_point_f
Not applicable
flash_point_c
Not applicable
ppe
Eyeshields, Gloves, multi-purpose combination respirator cartridge (US)
法规信息
新产品
此项目有
Andrew Nguyen et al.
The Journal of biological chemistry, 289(3), 1688-1703 (2013-12-03)
Obesity is associated with adipose tissue remodeling, characterized by adipocyte hypertrophy and macrophage infiltration. Previously, we have shown that very low density lipoprotein receptor (VLDLR) is virtually absent in preadipocytes but is strongly induced during adipogenesis and actively participates in
J Nimpf et al.
Biochimica et biophysica acta, 1529(1-3), 287-298 (2000-12-09)
The discovery of an ever growing number of low density lipoprotein (LDL) receptor gene family members has triggered research into many different directions. Here we first summarize the results of classical studies on the role of the LDL receptor in
Praseetha Kizhakkedath et al.
Biochimica et biophysica acta, 1843(12), 2871-2877 (2014-09-01)
Dysequilibrium syndrome (DES, OMIM 224050) is a genetically heterogeneous condition that combines autosomal recessive non-progressive cerebellar ataxia with mental retardation. The subclass dysequilibrium syndrome type 1 (CAMRQ1) has been attributed to mutations in the VLDLR gene encoding the very low
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