Anti-CCL28 antibody produced in chicken

CCL28 (chemokine ligand 28) is a CC chemokine, which is also known as mucosae-associated epithelial chemokine (MEC). It acts as a ligand for CCR10 and CCR3, and is expressed by specific mucosal tissues such as trachea, colon and exocrine glands. It has a constitutive expression in human salivary glands, and is present in high levels in human saliva and milk. Its C-terminal shares high sequence similarity with histatin-5, which is a candidacidal human saliva peptide rich in histidine.

Immunogen Sequence: GI # 9790211, sequence 65-120

Recombinant small inducible cytokine A28

Anti-CCL28 antibody produced in chicken is suitable for western blotting analysis at a dilution of 1:500, for tissue or cell staining at a dilution of 1:200.

Chemokine (C-C motif) ligand 28 (CCL28) acts as a novel growth factor that directly stimulates proliferation of primitive hematopoietic cells from different ontogenetic origins. It enhances the functional progenitor cell by stimulating cell cycling and induces gene expression changes associated with survival. CCL28 may contribute to the pathogenesis of atopic dermatitis (AD) and may act as an objective prognostic marker for disease severity. It may be useful for the diagnosis of cancer and may play a role in regulating mammary carcinogenesis. CCL28 gene absence may also contribute to the host′s immune response to tumors.

Solution in phosphate buffered saline containing 0.02% sodium azide.

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