GW21065
Anti-LTBR antibody produced in chicken
affinity isolated antibody, buffered aqueous solution
别名:
Anti-Lymphotoxin β receptor, Anti-TNFRSF3, Anti-Tumor necrosis factor receptor superfamily member 3
生物来源
chicken
偶联物
unconjugated
抗体形式
affinity isolated antibody
抗体产品类型
primary antibodies
克隆
polyclonal
表单
buffered aqueous solution
种属反应性
human
制造商/商品名称
Genway 15-288-21065
技术
western blot: suitable
NCBI登记号
UniProt登记号
运输
wet ice
储存温度
−20°C
靶向翻译后修饰
unmodified
基因信息
human ... LTBR(4055)
一般描述
LTBR (lymphotoxin β receptor) is a member of the tumor necrosis factor (TNF) superfamily, which also includes LTα and LTβ. It is expressed on stromal, parenchymal and myeloid cells. It is a part of the noncanonical/canonical nuclear factor-κB (NF-κB) signaling pathway.
应用
Anti-LTBR antibody produced in chicken is suitable for western blotting analysis at a dilution of 1:500, for tissue or cell staining at a dilution of 1:200.
生化/生理作用
Lymphotoxin β receptor signaling serves pleiotropic functions including the control of lymphoid organ development and support of efficient immune responses against pathogens. LTBR signaling induces chemokine, cytokine or adhesion molecule expression, cell proliferation and cell survival. LTBR is important for development and organization of the secondary lymphoid tissues and its polymorphisms may be associated with risk of IgA nephropathy (IgAN).
外形
Solution in phosphate buffered saline containing 0.02% sodium azide.
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储存分类代码
10 - Combustible liquids
WGK
WGK 1
闪点(°F)
Not applicable
闪点(°C)
Not applicable
个人防护装备
Eyeshields, Gloves, multi-purpose combination respirator cartridge (US)
法规信息
新产品
此项目有
M J Wolf et al.
Oncogene, 29(36), 5006-5018 (2010-07-07)
The cytokines lymphotoxin (LT) alpha, beta and their receptor (LTbetaR) belong to the tumor necrosis factor (TNF) superfamily, whose founder-TNFalpha-was initially discovered due to its tumor necrotizing activity. LTbetaR signaling serves pleiotropic functions including the control of lymphoid organ development
Su Kang Kim et al.
Immunological investigations, 41(5), 447-457 (2012-03-16)
Lymphotoxin beta receptor (LTBR) is essential for development and organization of the secondary lymphoid tissues. To investigate whether LTBR polymorphisms are associated with IgA nephropathy (IgAN) in Korean children, One hundred ninety nine patients with IgAN and 289 controls were
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