GW21068
Anti-MAP2K1 antibody produced in chicken
affinity isolated antibody, buffered aqueous solution
别名:
Anti-Dual specificity mitogen-activated protein kinase kinase 1, Anti-MEK1, Anti-Mitogen-activated protein kinase kinase 1
生物来源
chicken
偶联物
unconjugated
抗体形式
affinity isolated antibody
抗体产品类型
primary antibodies
克隆
polyclonal
表单
buffered aqueous solution
种属反应性
mouse, rat, human
制造商/商品名称
Genway 15-288-21068
技术
western blot: suitable
NCBI登记号
UniProt登记号
运输
wet ice
储存温度
−20°C
靶向翻译后修饰
unmodified
基因信息
human ... MAP2K1(5604)
免疫原
Immunogen Sequence: GI # 5579478, sequence 1-28
Recombinant mitogen-activated protein kinase kinase 1
应用
Anti-MAP2K1 antibody produced in chicken is suitable for western blotting analysis at a dilution of 1:500, for tissue or cell staining at a dilution of 1:200.
生化/生理作用
Dual specificity mitogen-activated protein kinase kinase 1 is an enzyme encoded by the MAP2K1 gene in humans and its signaling is one of the most important mechanisms for the cytoplasmic transduction of extracellular signals. MAP2K1 is mapped between chromosomes 15q22.1 and q22.33. It is induced with G2 phase MAPK pathway activation. MAP2K1 is associated with extracellular signal regulated kinases pathway and is involved in regulation of multiple cellular processes that include the cell cycle. Its inhibitors can partially modulate the expression of interferon-stimulated genes.
外形
Solution in phosphate buffered saline containing 0.02% sodium azide.
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储存分类代码
10 - Combustible liquids
WGK
WGK 1
闪点(°F)
Not applicable
闪点(°C)
Not applicable
个人防护装备
Eyeshields, Gloves, multi-purpose combination respirator cartridge (US)
法规信息
新产品
此项目有
Tanya Pike et al.
Cellular signalling, 25(6), 1423-1428 (2013-03-26)
The primary endpoint of signalling through the canonical Raf-MEK-ERK MAP kinase cascade is ERK activation. Here we report a novel signalling outcome for this pathway. Activation of the MAP kinase pathway by growth factors or phorbol esters during G2 phase
L Rampoldi et al.
Cytogenetics and cell genetics, 78(3-4), 301-303 (1997-01-01)
The mitogen-activated protein kinase (MAPK) signaling cascade is one of the most important mechanisms for the cytoplasmic transduction of extracellular signals. We report the chromosomal localization of the human MEK1, MEK3, MEK4 and MEKK5 genes, involved in the MAPK cascade.
Rongjuan Pei et al.
Virologica Sinica, 27(5), 278-285 (2012-09-25)
The mitogen activated protein kinases-extracellular signal regulated kinases (MAPK-ERK) pathway is involved in regulation of multiple cellular processes including the cell cycle. In the present study using a Huh7 cell line Con1 with an HCV replicon, we have shown that
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