GW21068
Anti-MAP2K1 antibody produced in chicken
affinity isolated antibody, buffered aqueous solution
别名:
Anti-Dual specificity mitogen-activated protein kinase kinase 1, Anti-MEK1, Anti-Mitogen-activated protein kinase kinase 1
biological source
chicken
conjugate
unconjugated
antibody form
affinity isolated antibody
antibody product type
primary antibodies
clone
polyclonal
form
buffered aqueous solution
species reactivity
mouse, rat, human
manufacturer/tradename
Genway 15-288-21068
technique(s)
western blot: suitable
NCBI accession no.
UniProt accession no.
shipped in
wet ice
storage temp.
−20°C
target post-translational modification
unmodified
Gene Information
human ... MAP2K1(5604)
Immunogen
Immunogen Sequence: GI # 5579478, sequence 1-28
Recombinant mitogen-activated protein kinase kinase 1
Application
Anti-MAP2K1 antibody produced in chicken is suitable for western blotting analysis at a dilution of 1:500, for tissue or cell staining at a dilution of 1:200.
Biochem/physiol Actions
Dual specificity mitogen-activated protein kinase kinase 1 is an enzyme encoded by the MAP2K1 gene in humans and its signaling is one of the most important mechanisms for the cytoplasmic transduction of extracellular signals. MAP2K1 is mapped between chromosomes 15q22.1 and q22.33. It is induced with G2 phase MAPK pathway activation. MAP2K1 is associated with extracellular signal regulated kinases pathway and is involved in regulation of multiple cellular processes that include the cell cycle. Its inhibitors can partially modulate the expression of interferon-stimulated genes.
Physical form
Solution in phosphate buffered saline containing 0.02% sodium azide.
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存储类别
10 - Combustible liquids
wgk
WGK 1
flash_point_f
Not applicable
flash_point_c
Not applicable
ppe
Eyeshields, Gloves, multi-purpose combination respirator cartridge (US)
法规信息
新产品
此项目有
Tanya Pike et al.
Cellular signalling, 25(6), 1423-1428 (2013-03-26)
The primary endpoint of signalling through the canonical Raf-MEK-ERK MAP kinase cascade is ERK activation. Here we report a novel signalling outcome for this pathway. Activation of the MAP kinase pathway by growth factors or phorbol esters during G2 phase
L Rampoldi et al.
Cytogenetics and cell genetics, 78(3-4), 301-303 (1997-01-01)
The mitogen-activated protein kinase (MAPK) signaling cascade is one of the most important mechanisms for the cytoplasmic transduction of extracellular signals. We report the chromosomal localization of the human MEK1, MEK3, MEK4 and MEKK5 genes, involved in the MAPK cascade.
Rongjuan Pei et al.
Virologica Sinica, 27(5), 278-285 (2012-09-25)
The mitogen activated protein kinases-extracellular signal regulated kinases (MAPK-ERK) pathway is involved in regulation of multiple cellular processes including the cell cycle. In the present study using a Huh7 cell line Con1 with an HCV replicon, we have shown that
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