Anti-RIPK1 antibody produced in chicken

Immunogen Sequence: GI # 4506539, sequence 337-525

Recombinant receptor (TNFRSF)-interacting serine-threonine kinase 1

Anti-RIPK1 antibody produced in chicken is suitable for western blotting analysis at a dilution of 1:500, for tissue or cell staining at a dilution of 1:200.

Receptor-interacting serine/threonine-protein kinase 1 is an enzyme encoded by RIPK1 gene in humans. It is a multifunctional protein containing an N-terminal Ser/Thr kinase and a C-terminal death domain. RIPK1 acts as a key regulatory molecule involved in regulating both cell death and cell survival. It plays an important role in regulating multiple cellular mechanisms, its dynamic regulation, the physiological and pathological roles of RIP1 kinase in human health and disease. RIP1 is an essential upstream signaling molecule in tumor-necrosis-factor-α-induced necroptosis. It is a novel form of apoptosis-inducing protein and participates in the TNF signaling cascades leading to apoptosis and NF-κB activation.

Solution in phosphate buffered saline containing 0.02% sodium azide.

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