biological source
chicken
conjugate
unconjugated
antibody form
affinity isolated antibody
antibody product type
primary antibodies
clone
polyclonal
form
buffered aqueous solution
species reactivity
human
technique(s)
western blot: suitable
NCBI accession no.
UniProt accession no.
shipped in
wet ice
storage temp.
−20°C
Gene Information
human ... PSAT1(29968)
Immunogen
Immunogen Sequence: GI # 17402893, sequence 290-340
Recombinant phosphoserine aminotransferase isoform 1
Application
Anti-PSAT1 antibody produced in chicken is suitable for western blotting analysis at a dilution of 1:500, for tissue or cell staining at a dilution of 1:200.
Biochem/physiol Actions
Phosphohydroxythreonine aminotransferase (PSAT) is an enzyme encoded by the PSAT1 gene in humans. It may be implicated in altered serine metabolism and schizophrenia spectrum conditions. PSAT plays a role in the L-serine biosynthesis that could be implicated in colon cancer progression and chemoresistance. It can act as a new interesting target for colorectal cancer (CRC) therapy. Human PSAT gene is regulated depending on tissue specificity and cellular proliferation status with a maximum level expression in the S-phase.
Physical form
Solution in phosphate buffered saline containing 0.02% sodium azide.
Disclaimer
Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.
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存储类别
10 - Combustible liquids
wgk
WGK 1
flash_point_f
Not applicable
flash_point_c
Not applicable
ppe
Eyeshields, Gloves, multi-purpose combination respirator cartridge (US)
法规信息
新产品
此项目有
Yuji Ozeki et al.
Neuroscience research, 69(2), 154-160 (2010-10-20)
l-Serine is required for the synthesis of glycine and d-serine, both of which are NMDA receptor co-agonists. Although roles for d-serine and glycine have been suggested in schizophrenia, little is known about the role of the l-serine synthesizing cascade in
Joo Youn Baek et al.
The Biochemical journal, 373(Pt 1), 191-200 (2003-03-14)
In the present study, we first report two forms of human phosphoserine aminotransferase (PSAT) cDNA (HsPSAT alpha and HsPSAT beta). HsPSAT alpha has a predicted open reading frame comprising 324 amino acids, encoding a 35.2 kDa protein (PSAT alpha), whereas
Nadia Vié et al.
Molecular cancer, 7, 14-14 (2008-01-29)
Colorectal cancer (CRC) is one of the most common causes of cancer death throughout the world. In this work our aim was to study the role of the phosphoserine aminotransferase PSAT1 in colorectal cancer development. We first observed that PSAT1
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