生物来源
chicken
偶联物
unconjugated
抗体形式
affinity isolated antibody
抗体产品类型
primary antibodies
克隆
polyclonal
表单
buffered aqueous solution
种属反应性
human
技术
western blot: suitable
NCBI登记号
UniProt登记号
运输
wet ice
储存温度
−20°C
基因信息
human ... PSAT1(29968)
免疫原
Immunogen Sequence: GI # 17402893, sequence 290-340
Recombinant phosphoserine aminotransferase isoform 1
应用
Anti-PSAT1 antibody produced in chicken is suitable for western blotting analysis at a dilution of 1:500, for tissue or cell staining at a dilution of 1:200.
生化/生理作用
Phosphohydroxythreonine aminotransferase (PSAT) is an enzyme encoded by the PSAT1 gene in humans. It may be implicated in altered serine metabolism and schizophrenia spectrum conditions. PSAT plays a role in the L-serine biosynthesis that could be implicated in colon cancer progression and chemoresistance. It can act as a new interesting target for colorectal cancer (CRC) therapy. Human PSAT gene is regulated depending on tissue specificity and cellular proliferation status with a maximum level expression in the S-phase.
外形
Solution in phosphate buffered saline containing 0.02% sodium azide.
免责声明
Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.
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储存分类代码
10 - Combustible liquids
WGK
WGK 1
闪点(°F)
Not applicable
闪点(°C)
Not applicable
个人防护装备
Eyeshields, Gloves, multi-purpose combination respirator cartridge (US)
法规信息
新产品
此项目有
Yuji Ozeki et al.
Neuroscience research, 69(2), 154-160 (2010-10-20)
l-Serine is required for the synthesis of glycine and d-serine, both of which are NMDA receptor co-agonists. Although roles for d-serine and glycine have been suggested in schizophrenia, little is known about the role of the l-serine synthesizing cascade in
Joo Youn Baek et al.
The Biochemical journal, 373(Pt 1), 191-200 (2003-03-14)
In the present study, we first report two forms of human phosphoserine aminotransferase (PSAT) cDNA (HsPSAT alpha and HsPSAT beta). HsPSAT alpha has a predicted open reading frame comprising 324 amino acids, encoding a 35.2 kDa protein (PSAT alpha), whereas
Nadia Vié et al.
Molecular cancer, 7, 14-14 (2008-01-29)
Colorectal cancer (CRC) is one of the most common causes of cancer death throughout the world. In this work our aim was to study the role of the phosphoserine aminotransferase PSAT1 in colorectal cancer development. We first observed that PSAT1
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