Anti-EWSR1 antibody produced in chicken

Immunogen Sequence: GI # 4885225, sequence 380-448

Recombinant ewing sarcoma breakpoint region 1 isoform EWS

Anti-EWSR1 antibody produced in chicken is suitable for western blotting analysis at a dilution of 1:500, for tissue or cell staining at a dilution of 1:200.

RNA-binding protein EWS is a protein encoded by the EWSR1 gene in humans and is located on human chromosome 22. It is involved in a wide variety of sarcomas as well as some non-mesenchymal tumours. EWSR1 is a ′promiscuous′ gene that can fuse with many different partner genes, resulting in identical tumours. It can partner with the same genes in morphologically and behaviourally different neoplasms. EWSR1 rearrangement is also associated with a variety of salivary gland lesions including classic myoepitheliomas and hyalinizing clear cell carcinomas (HCCCs). It also acts as a novel modulator of cis-acting replication element (CRE) function in hepatitis C virus (HCV) replication.

Solution in phosphate buffered saline containing 0.02% sodium azide.

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