生物来源
chicken
偶联物
unconjugated
抗体形式
affinity isolated antibody
抗体产品类型
primary antibodies
克隆
polyclonal
表单
buffered aqueous solution
种属反应性
rat, human, mouse
制造商/商品名称
Genway 15-288-22390A
技术
indirect ELISA: suitable
western blot: suitable
NCBI登记号
UniProt登记号
运输
wet ice
储存温度
−20°C
基因信息
human ... MAT2A(4144)
应用
Anti-MAT2A antibody produced in chicken is suitbale for indirect ELISA and western blotting analysis at a dilution of 1:500, for tissue or cell staining at a dilution of 1:200.
生化/生理作用
Methionine adenosyltransferase (MAT) is an enzyme responsible for S-adenosylmethionine (AdoMet) synthesis and is encoded by two genes, MAT1A and MAT2A. MAT1A and MAT2A encode for liver-specific and non-liver-specific MAT respectively. MAT2A expression is associated with lower AdoMet levels and a dedifferentiated phenotype. The gene expression is modulated as an adaptive response of the cell to l-methionine availability through its conversion to AdoMet. MAT2A is involved in the transmethylation pathway in the metabolic response to hyperoxia in lung epithelium.
外形
Solution in phosphate buffered saline containing 0.02% sodium azide.
免责声明
Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.
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储存分类代码
10 - Combustible liquids
WGK
WGK 1
闪点(°F)
Not applicable
闪点(°C)
Not applicable
个人防护装备
Eyeshields, Gloves, multi-purpose combination respirator cartridge (US)
法规信息
新产品
此项目有
Maria L Martínez-Chantar et al.
The Journal of biological chemistry, 278(22), 19885-19890 (2003-03-28)
In mammals, methionine adenosyltransferase (MAT), the enzyme responsible for S-adenosylmethionine (AdoMet) synthesis, is encoded by two genes, MAT1A and MAT2A. In liver, MAT1A expression is associated with high AdoMet levels and a differentiated phenotype, whereas MAT2A expression is associated with
Z Mao et al.
Biochemical and biophysical research communications, 248(3), 479-484 (1998-08-15)
Methionine adenosyltransferase (MAT) is a critical cellular enzyme which catalyzes the formation of S-adenosylmethionine, the principal methyl donor. In mammals, two different genes, MAT1A and MAT2A, encode for liver-specific and non-liver-specific MAT, respectively. We have cloned and characterized a 1.4-kb
Mihalis I Panayiotidis et al.
Free radical biology & medicine, 40(2), 348-358 (2006-01-18)
S-Adenosylmethionine (SAM, AdoMet) is the most important methyl donor used for synthesis of nucleic acids, phospholipids, creatine, and polyamines and for methylation of many bioactive molecules. The metabolic response of the lung to oxidative stress of hyperoxia requires increased RNA
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