Anti-Integrin β1 antibody produced in chicken

Immunogen Sequence: GI # 19743823, sequence 21-140

Recombinant integrin β 1 isoform 1A

Anti-Integrin β1 antibody produced in chicken was used in western blot analysis of amoeba whole-cell lysates and membrane fractions for the detection of integrin-like proteins. It is also suitable for western blotting analysis at a dilution of 1:500, for tissue or cell staining at a dilution of 1:200.

Integrin β-1 is a protein encoded by the ITGB1 gene in humans and regulates multiple epithelial cell functions by connecting cells with the extracellular matrix. It helps in enhancing epithelial-to-mesenchymal transition (EMT) through FAK-AKT signaling pathway. The protein expression may have potential in identifying the stage of colorectal liver metastases and may act as a marker of prognosis in these patients.

Solution in phosphate buffered saline containing 0.02% sodium azide.

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