biological source
chicken
conjugate
unconjugated
antibody form
affinity isolated antibody
antibody product type
primary antibodies
clone
polyclonal
form
buffered aqueous solution
species reactivity
human
manufacturer/tradename
Genway 15-288-22758
technique(s)
western blot: suitable
NCBI accession no.
UniProt accession no.
shipped in
wet ice
storage temp.
−20°C
Gene Information
human ... STAT1(6772)
Immunogen
Immunogen Sequence: GI # 21536301, sequence 51-235
Recombinant signal transducer and activator of transcription 1 isoform β
Application
Anti-STAT1 (ab1) antibody produced in chicken is suitable for western blotting analysis at a dilution of 1:500, for tissue or cell staining at a dilution of 1:200.
Biochem/physiol Actions
STAT1 is a member of the ′Signal Transducers and Activators of Transcription′ family of transcription factors and is involved in upregulating genes in response to signals by either type I, type II or type III interferons. STAT1 may be a target for therapeutic intervention, with the intention to restore apoptotic mechanisms and sensitivity to chemotherapy. P-STAT1 is a potential predictor of interferon (IFN) response for advanced renal cell carcinoma. Mutations in the gene is associated with death at an early age due to overwhelming viral infection (complete STAT1 deficiency).
Physical form
Solution in phosphate buffered saline containing 0.02% sodium azide.
Disclaimer
Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.
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存储类别
12 - Non Combustible Liquids
wgk
WGK 1
flash_point_f
Not applicable
flash_point_c
Not applicable
ppe
Eyeshields, Gloves, multi-purpose combination respirator cartridge (US)
法规信息
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相关内容
Instructions
Wei Li et al.
Molecular medicine reports, 9(5), 1929-1934 (2014-03-15)
The present study aimed to evaluate the expression status of Janus kinase (JAK)-Signal Transducer and Activator of Transcription (STAT) in renal cell carcinoma and benign renal tissue, and identify a potential biomarker for interferon (IFN) response prediction. A total of
Lisa Arzt et al.
Virchows Archiv : an international journal of pathology, 465(1), 79-88 (2014-05-20)
Malignant pleural mesothelioma (MPM) is the most common primary tumor of the pleura. Its incidence is increasing in Europe and the prognosis remains poor. We compared epithelioid MPM in short and long survivors, and identified signal transducer and activator of
Nigel Sharfe et al.
The Journal of allergy and clinical immunology, 133(3), 807-817 (2013-11-19)
Mutations in the gene for the signal transducer and activator of transcription 1, STAT1, have been shown to be associated with death at an early age due to overwhelming viral infection (complete STAT1 deficiency) or, more commonly, selective deficiencies to