Anti-GAPDH antibody produced in chicken

Immunogen Sequence: GI # 7669492, sequence 51-290

Recombinant glyceraldehyde-3-phosphate dehydrogenase

Anti-GAPDH antibody produced in chicken is suitable for western blotting analysis at a dilution of 1:500, for tissue or cell staining at a dilution of 1:200.

Applications in which this antibody has been used successfully, and the associated peer-reviewed papers, are given below.
Western Blotting (1 paper)

Glyceraldehyde 3-phosphate dehydrogenase (G3PDH) is an enzyme that catalyzes the sixth step of glycolysis and serves to break down glucose for energy and carbon molecules. It is an obligatory enzyme in glycolysis and performs a critical role in cellular regulation. GAPDH also plays a critical role in apoptosis and age-related neurodegenerative diseases, such as Alzheimer′s, Huntington′s and Parkinson′s diseases. Overexpression of this gene in resected tumor samples is an adverse prognostic factor in non-small cell lung cancers (NSCLC). It is used as a stable housekeeping marker for constant gene expression and its transcriptional levels may be highly up-regulated in some cancers.

Solution in phosphate buffered saline containing 0.02% sodium azide.

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