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Merck
CN

GW22833

Sigma-Aldrich

Anti-α-2-Catenin antibody produced in chicken

affinity isolated antibody, buffered aqueous solution

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UNSPSC代码:
12352203
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生物来源

chicken

偶联物

unconjugated

抗体形式

affinity isolated antibody

抗体产品类型

primary antibodies

克隆

polyclonal

表单

buffered aqueous solution

种属反应性

mouse, rat, human

制造商/商品名称

Genway 15-288-22833

技术

western blot: suitable

NCBI登记号

UniProt登记号

运输

wet ice

储存温度

−20°C

基因信息

human ... CTNNA2(1496)

免疫原

Immunogen Sequence: GI # 7656999, sequence 141-300
Recombinant catenin, α 2

应用

Anti-α-2-Catenin antibody produced in chicken is suitable for western blotting analysis at a dilution of 1:500, for tissue or cell staining at a dilution of 1:200.

生化/生理作用

CTNNA2 encodes α-catenin 2 and is mapped to the p11.1-p12 region of human chromosome 2. The gene encodes for a brain-expressed α-catenin that is critical for synaptic contact. It is differentially regulated by smoking in schizophrenic patients. The differences in gene expression in postmortem brain of schizophrenic non-smokers implicates this gene in the disease. It is a tumour suppressor gene frequently mutated in laryngeal carcinomas.

外形

Solution in phosphate buffered saline containing 0.02% sodium azide.

免责声明

Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.

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储存分类代码

12 - Non Combustible Liquids

WGK

WGK 1

闪点(°F)

Not applicable

闪点(°C)

Not applicable

个人防护装备

Eyeshields, Gloves, multi-purpose combination respirator cartridge (US)

法规信息

新产品
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历史批次信息供参考:

分析证书(COA)

Lot/Batch Number

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Sharon Mexal et al.
American journal of medical genetics. Part B, Neuropsychiatric genetics : the official publication of the International Society of Psychiatric Genetics, 147B(6), 759-768 (2008-01-01)
The alphaN-catenin (CTNNA2) gene represents a promising candidate gene for schizophrenia based upon previous genetic linkage, expression, and mouse knockout studies. CTNNA2 is differentially regulated by smoking in schizophrenic patients. In this report, the genomic structure of a primate-specific alphaN-catenin
J M Claverie et al.
Genomics, 15(1), 13-20 (1993-01-01)
We report the characterization of a human cDNA encompassing the complete coding region of a 945-residue putative protein (CAP-R) 80% identical to the recently described murine 102-kDa alpha-catenin (CAP102). The CAP-R protein mostly differs from CAP102 by the presence of
A Terracciano et al.
Translational psychiatry, 1, e49-e49 (2011-01-01)
The tendency to seek stimulating activities and intense sensations define excitement-seeking, a personality trait akin to some aspects of sensation-seeking. This trait is a central feature of extraversion and is a component of the multifaceted impulsivity construct. Those who score
Miriam Fanjul-Fernández et al.
Nature communications, 4, 2531-2531 (2013-10-09)
Laryngeal squamous cell carcinoma is a frequent and significant cause of morbidity and mortality. Here we explore the biological basis of this aggressive tumour, and identify two cell-cell adhesion genes as recurrently mutated in this malignancy. We first perform exome

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