Anti-RGS18 antibody produced in chicken

Immunogen Sequence: GI # 18640750, sequence 11-100

Recombinant regulator of G-protein signalling 18

Anti-RGS18 antibody produced in chicken is suitable for western blotting analysis at a dilution of 1:500, for tissue or cell staining at a dilution of 1:200.

Regulator of G-protein signaling 18 is a protein encoded by the RGS18 gene in humans. It is a GTPase-activating protein for the G-α-q and G-α-i subunits of heterotrimeric G-proteins that turns off signaling by G-protein coupled receptors. It is highly expressed in platelets. RGS18 can act on G(q)-mediated signaling pathways. It is expressed most highly in megakaryocytes and can modulate GPCR pathways in both mammalian and yeast cells. RGS18 may have an important role in the regulation of megakaryocyte differentiation and chemotaxis.

Solution in phosphate buffered saline containing 0.02% sodium azide.

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