H1392
骆驼蓬灵 盐酸盐 二水合物
≥95%
别名:
1-甲基-7-甲氧基-3,4-二氢-β-咔啉 盐酸盐
方案
≥95%
drug control
stupéfiant (France); regulated under CDSA - not available from Sigma-Aldrich Canada
应用
forensics and toxicology
储存温度
−20°C
SMILES字符串
Cl[H].[H]O[H].[H]O[H].COc1ccc2c3CCN=C(C)c3[nH]c2c1
InChI
1S/C13H14N2O.ClH.2H2O/c1-8-13-11(5-6-14-8)10-4-3-9(16-2)7-12(10)15-13;;;/h3-4,7,15H,5-6H2,1-2H3;1H;2*1H2
InChI key
LCEKUHFBUFUSSY-UHFFFAOYSA-N
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生化/生理作用
中枢神经系统兴奋剂;可通过 NMDA 受体起作用
警示用语:
Warning
危险声明
危险分类
Acute Tox. 4 Oral - STOT SE 2
靶器官
Central nervous system
储存分类代码
11 - Combustible Solids
WGK
WGK 3
闪点(°F)
Not applicable
闪点(°C)
Not applicable
个人防护装备
Eyeshields, Gloves, type N95 (US)
法规信息
监管及禁止进口产品
Barbara Kosmowska et al.
Neurochemical research, 45(7), 1518-1525 (2020-03-17)
Essential tremor is one of the most common neurological disorders, however, it is not sufficiently controlled with currently available pharmacotherapy. Our recent study has shown that pramipexole, a drug efficient in inhibiting parkinsonian tremor, reduced the harmaline-induced tremor in rats
Sarah Eller et al.
Forensic science international, 312, 110298-110298 (2020-05-11)
Ayahuasca is a beverage composed by a mixture of herbs which contain the compound N,N-dimethyltriptamine (DMT) and the β-carbolines. Although its use is legalized in Brazil only for religious and spiritual ceremonies, there is a growing black market specialized in
Fatemeh Mohammadi et al.
Neuroscience letters, 704, 153-158 (2019-04-12)
There are conflicting reports concerning the association of motor disabilities with increased risk of mental disorders. This investigation will provide a good understanding about defining the possible association between tremor and risk of anxiety and cognitive alterations. Beside, a secondary
Amanda M Brown et al.
eLife, 9 (2020-03-18)
Tremor is currently ranked as the most common movement disorder. The brain regions and neural signals that initiate the debilitating shakiness of different body parts remain unclear. Here, we found that genetically silencing cerebellar Purkinje cell output blocked tremor in
Hassan Abbassian et al.
British journal of pharmacology, 173(22), 3196-3207 (2016-10-21)
Essential tremor (ET) is a neurological disorder with unknown aetiology. Its symptoms include cerebellar motor disturbances, cognitive and personality changes, hearing and olfactory deficits. Hyperactivity of excitotoxic cerebellar climbing fibres may underlie essential tremor and has been induced in rodents
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