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Merck
CN

H1392

骆驼蓬灵 盐酸盐 二水合物

≥95%

别名:

1-甲基-7-甲氧基-3,4-二氢-β-咔啉 盐酸盐

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关于此项目

经验公式(希尔记法):
C13H14N2O · HCl · 2H2O
化学文摘社编号:
分子量:
286.75
UNSPSC Code:
12352200
NACRES:
NA.25
PubChem Substance ID:
MDL number:
Beilstein/REAXYS Number:
6493114
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InChI

1S/C13H14N2O.ClH.2H2O/c1-8-13-11(5-6-14-8)10-4-3-9(16-2)7-12(10)15-13;;;/h3-4,7,15H,5-6H2,1-2H3;1H;2*1H2

SMILES string

Cl[H].[H]O[H].[H]O[H].COc1ccc2c3CCN=C(C)c3[nH]c2c1

InChI key

LCEKUHFBUFUSSY-UHFFFAOYSA-N

assay

≥95%

drug control

stupéfiant (France); regulated under CDSA - not available from Sigma-Aldrich Canada

application(s)

forensics and toxicology

storage temp.

−20°C

Biochem/physiol Actions

中枢神经系统兴奋剂;可通过 NMDA 受体起作用

pictograms

Health hazardExclamation mark

signalword

Warning

hcodes

Hazard Classifications

Acute Tox. 4 Oral - STOT SE 2

target_organs

Central nervous system

存储类别

11 - Combustible Solids

wgk

WGK 3

flash_point_f

Not applicable

flash_point_c

Not applicable

ppe

Eyeshields, Gloves, type N95 (US)

法规信息

涉药品监管产品
此项目有

历史批次信息供参考:

分析证书(COA)

Lot/Batch Number

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Neurochemical research, 45(7), 1518-1525 (2020-03-17)
Essential tremor is one of the most common neurological disorders, however, it is not sufficiently controlled with currently available pharmacotherapy. Our recent study has shown that pramipexole, a drug efficient in inhibiting parkinsonian tremor, reduced the harmaline-induced tremor in rats
Fatemeh Mohammadi et al.
Neuroscience letters, 704, 153-158 (2019-04-12)
There are conflicting reports concerning the association of motor disabilities with increased risk of mental disorders. This investigation will provide a good understanding about defining the possible association between tremor and risk of anxiety and cognitive alterations. Beside, a secondary
Sarah Eller et al.
Forensic science international, 312, 110298-110298 (2020-05-11)
Ayahuasca is a beverage composed by a mixture of herbs which contain the compound N,N-dimethyltriptamine (DMT) and the β-carbolines. Although its use is legalized in Brazil only for religious and spiritual ceremonies, there is a growing black market specialized in
Hassan Abbassian et al.
British journal of pharmacology, 173(22), 3196-3207 (2016-10-21)
Essential tremor (ET) is a neurological disorder with unknown aetiology. Its symptoms include cerebellar motor disturbances, cognitive and personality changes, hearing and olfactory deficits. Hyperactivity of excitotoxic cerebellar climbing fibres may underlie essential tremor and has been induced in rodents
Amanda M Brown et al.
eLife, 9 (2020-03-18)
Tremor is currently ranked as the most common movement disorder. The brain regions and neural signals that initiate the debilitating shakiness of different body parts remain unclear. Here, we found that genetically silencing cerebellar Purkinje cell output blocked tremor in

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