H1763
Hippuryl-Gly-Gly
别名:
N-Benzoyl-Gly-Gly-Gly
方案
≥99% (HPLC)
表单
powder
溶解性
1 M NH4OH: 50 mg/mL, clear, colorless
储存温度
−20°C
SMILES字符串
OC(=O)CNC(=O)CNC(=O)CNC(=O)c1ccccc1
InChI
1S/C13H15N3O5/c17-10(15-8-12(19)20)6-14-11(18)7-16-13(21)9-4-2-1-3-5-9/h1-5H,6-8H2,(H,14,18)(H,15,17)(H,16,21)(H,19,20)
InChI key
CYQZRSVDAIOAIY-UHFFFAOYSA-N
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一般描述
Substrate for angiotensin converting enzyme (ACE)
法规信息
新产品
此项目有
T A Stewart et al.
Peptides, 2(2), 145-152 (1981-01-01)
We purified peptidyl-dipeptidase (converting enzyme, EC 3.4.15.1) to homogeneity from the membrane fraction of human lung and for comparison, from human and hog kidney. The membrane-bound lung enzyme was purified 1800-fold with 19% yield, and the kidney enzyme 640-fold with
Simple radioassay for measuring serum activity of angiotensin-converting enzyme in sarcoidosis.
P K Rohatgi et al.
Chest, 78(1), 69-76 (1980-07-01)
L Mor et al.
Journal of pharmacological methods, 23(2), 141-153 (1990-04-01)
We have developed a pressure-dependent isolated lung perfusion system that can be used for the determination of pulmonary enzyme activity and kinetics under physiologic conditions. This development was done using two different artificial radiolabeled substrates, glycine-1-hippuryl-L-histidyl-L-leucine and phenyl-4(n)-hippuryl-glycyl-glycine, for the
Characterization of a dipeptide hydrolase (kininase II: angiotensin I converting enzyme).
H Y Yang et al.
The Journal of pharmacology and experimental therapeutics, 177(1), 291-300 (1971-04-01)
J Marchetti et al.
Kidney international, 31(3), 744-751 (1987-03-01)
Angiotensin I converting enzyme (ACE) and kininase activities were measured in various segments of the rabbit nephron. ACE was determined with tritiated hippuryl-glycylglycine as substrate. Lysyl-bradykinin (LBK) hydrolysis (kininase activity) was measured by radioimmunoassay. ACE was only found in the
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