H2161
8-Hydroxyadenosine-3′,5′-monophosphorothioate, Rp-isomer
>99% (HPLC), solid
SMILES string
Nc1ncnc2n([C@@H]3O[C@@H]4CO[P@@](S)(=O)O[C@H]4[C@H]3O)c(O)nc12
InChI
1S/C10H12N5O6PS/c11-7-4-8(13-2-12-7)15(10(17)14-4)9-5(16)6-3(20-9)1-19-22(18,23)21-6/h2-3,5-6,9,16H,1H2,(H,14,17)(H,18,23)(H2,11,12,13)/t3-,5-,6-,9-,22-/m1/s1
InChI key
ZJLRJSRRXWDPOZ-KVBUDSETSA-N
biological source
synthetic (organic)
assay
>99% (HPLC)
form
solid
mol wt
390.26
packaging
vial of 1 μmol (approx. 0.4mg)
storage temp.
−20°C
Quality Level
Biochem/physiol Actions
Phosphodiesterase-resistant, polar, membrane-impermeable inhibitor of cAMP-dependent protein kinase (PKA).
存储类别
11 - Combustible Solids
wgk
WGK 3
flash_point_f
Not applicable
flash_point_c
Not applicable
ppe
Eyeshields, Gloves, type N95 (US)
法规信息
新产品
此项目有
Alexander Puzenko et al.
The Journal of chemical physics, 137(19), 194502-194502 (2012-11-28)
In this, the third part of our series on the dielectric spectrum symmetrical broadening of water, we consider the nucleotide aqueous solutions. Where in Parts I [E. Levy et al., J. Chem. Phys. 136, 114502 (2012)] and II [E. Levy
B T Gjertsen et al.
The Journal of biological chemistry, 270(35), 20599-20607 (1995-09-01)
Novel (Rp)-cAMPS analogs differed widely in ability to antagonize cAMP activation of pure cAMP-dependent protein kinase I and II and to antagonize actions of cAMP on gene expression, shape change, apoptosis, DNA replication, and protein phosphorylation in intact cells. These
我们的科学家团队拥有各种研究领域经验，包括生命科学、材料科学、化学合成、色谱、分析及许多其他领域.
联系客户支持