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Merck
CN

H2648

Hetastarch

6% in 0.9% NaCl

别名:

Hydroxyethyl starch, Hydroxyethylated amylopectin

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化学文摘社编号:
UNSPSC Code:
12352201
MDL number:
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SMILES string

OC[C@H]1O[C@H](O)[C@H](O)[C@@H](O)[C@@H]1O.OCCOC[C@H]2O[C@H](OCCO)[C@H](OCCO)[C@@H](OCCO)[C@@H]2OCCO

sterility

aseptically filled

concentration

6% in 0.9% NaCl

法规信息

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Pablo Perel et al.
The Cochrane database of systematic reviews, 2(2), CD000567-CD000567 (2013-03-02)
Colloid solutions are widely used in fluid resuscitation of critically ill patients. There are several choices of colloid, and there is ongoing debate about the relative effectiveness of colloids compared to crystalloid fluids. To assess the effects of colloids compared
Europe recommends ban on common plasma substitute.
Jacqui Wise
BMJ (Clinical research ed.), 346, f3942-f3942 (2013-06-19)
Andy Parrish et al.
South African medical journal = Suid-Afrikaanse tydskrif vir geneeskunde, 103(6), 365-367 (2013-06-04)
Recent trials have failed to demonstrate a survival benefit from the use of hydroxyethyl starches (HES) as a colloid in fluid resuscitation and have raised concerns of renal harm. In severe sepsis, there is a concerning signal of increased mortality.
NHS should ban use of starch based intravenous fluids, say researchers.
Jacqui Wise
BMJ (Clinical research ed.), 346, f1323-f1323 (2013-03-01)
Hydroxyethyl starch for intravenous volume replacement: more harm than benefit.
Massimo Antonelli et al.
JAMA, 309(7), 723-724 (2013-02-21)

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