H3635
γ-Hydroxybutyric acid sodium salt
别名:
4-Hydroxybutyric acid sodium salt, γ-Hydroxybutyric acid sodium salt, GHB, Sodium 4-hydroxybutyrate
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线性分子式:
HO(CH2)3COONa
化学文摘社编号:
分子量:
126.09
PubChem Substance ID:
UNSPSC Code:
12352200
NACRES:
NA.77
EC Number:
207-953-3
MDL number:
Beilstein/REAXYS Number:
3709170
SMILES string
[Na+].OCCCC([O-])=O
drug control
USDEA Schedule I; Home Office Schedule 4.1; stupéfiant (France); kontrollierte Droge in Deutschland; regulated under CDSA - not available from Sigma-Aldrich Canada; Pszichotróp anyag / Psychotropic Substance (Hungary), 78/2022. (XII. 28.) BM rendelet, kontrollierte Droge in Deutschland
Biochem/physiol Actions
Endogenous GABA analog that induces absence-like seizures. It blocks dopamine release by blocking impulse flow in dopaminergic neurons.
Legal Information
German
Dieses Produkt fällt unter das Betäubungsmittelgesetz (BtMG). Für eine Bestellung dieses Produktes ist eine Erlaubnis nach § 3 BtMG zwingend erforderlich, es sei denn, es greift eine Ausnahme von der Erlaubnispflicht nach § 4 oder § 26 BtMG.
English
This product is subject to the German Narcotics Act. A permit under Section 3 of the German Narcotics Act is mandatory for ordering this product unless an exemption from the permit requirement under Section 4 or Section 26 of the German Narcotics Act applies.
Dieses Produkt fällt unter das Betäubungsmittelgesetz (BtMG). Für eine Bestellung dieses Produktes ist eine Erlaubnis nach § 3 BtMG zwingend erforderlich, es sei denn, es greift eine Ausnahme von der Erlaubnispflicht nach § 4 oder § 26 BtMG.
English
This product is subject to the German Narcotics Act. A permit under Section 3 of the German Narcotics Act is mandatory for ordering this product unless an exemption from the permit requirement under Section 4 or Section 26 of the German Narcotics Act applies.
存储类别
13 - Non Combustible Solids
wgk
WGK 2
flash_point_f
Not applicable
flash_point_c
Not applicable
ppe
Eyeshields, Gloves, type N95 (US)
法规信息
监管及禁止进口产品
此项目有
M Hernandez et al.
The American journal of drug and alcohol abuse, 24(1), 179-183 (1998-03-26)
We describe what we believe is the first psychiatric hospitalization due to GHB-induced delirium reported in the medical literature. We examine the use of the substance gamma hydroxybutyric acid (GHB) and describe the clinical findings in a patient who presented
G Tunnicliff
General pharmacology, 23(6), 1027-1034 (1992-11-01)
1. Administration of the endogenous compound gamma-hydroxybutyric acid (GHB) can induce a sleep-like state in experimental animals and, indeed, it has been used as a general anaesthetic in clinical medicine. 2. Although GHB appears to be a CNS depressant, there
Wan-Ding Ong et al.
Journal of food science, 80(1), E93-E100 (2014-12-23)
Oil-in-water (O/W) emulsion-gel systems containing high oil payloads are of increasing interest for food applications because of the reduction in encapsulation cost, consumption frequency or volume of food products. This study shows a facile approach to prepare stable alginate-based O/W
Sarah Wurts Black et al.
The Journal of neuroscience : the official journal of the Society for Neuroscience, 34(19), 6485-6494 (2014-05-09)
γ-Hydroxybutyrate (GHB) is an approved therapeutic for the excessive sleepiness and sudden loss of muscle tone (cataplexy) characteristic of narcolepsy. The mechanism of action for these therapeutic effects is hypothesized to be GABAB receptor dependent. We evaluated the effects of
Jae Seong Lee et al.
Journal of biotechnology, 161(1), 34-41 (2012-06-26)
Previous research showed that co-down-regulation of caspase-3/7 in rCHO cells, unlike Bcl-2 overexpression, did not effectively block apoptotic cell death induced by 3mM sodium butyrate (NaBu). Here, it is found that the control of autophagy is also related to this
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