H3899
D-Homocysteinesulfinic acid
≥98% (TLC)
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关于此项目
经验公式（希尔记法）:
C4H9NO4S
化学文摘社编号:
分子量:
167.18
UNSPSC Code:
12352200
PubChem Substance ID:
MDL number:
assay
≥98% (TLC)
storage temp.
−20°C
SMILES string
NC(CCS(O)=O)C(O)=O
InChI
1S/C4H9NO4S/c5-3(4(6)7)1-2-10(8)9/h3H,1-2,5H2,(H,6,7)(H,8,9)
InChI key
PDNJLMZEGXHSCU-UHFFFAOYSA-N
Biochem/physiol Actions
Potent, fast-acting NMDA glutamate receptor agonist.
signalword
Warning
hcodes
Hazard Classifications
Eye Irrit. 2 - Skin Irrit. 2 - STOT SE 3
target_organs
Respiratory system
存储类别
11 - Combustible Solids
wgk
WGK 3
flash_point_f
Not applicable
flash_point_c
Not applicable
ppe
dust mask type N95 (US), Eyeshields, Gloves
法规信息
新产品
此项目有
W Morishita et al.
Journal of neurophysiology, 82(5), 2556-2564 (1999-11-24)
Depolarization-induced suppression of inhibition (DSI) is a process whereby brief approximately 1-s depolarization to the postsynaptic membrane of hippocampal CA1 pyramidal cells results in a transient suppression of GABA(A)ergic synaptic transmission. DSI is triggered by a postsynaptic rise in [Ca(2+)](in)
G A Thompson et al.
Neuropharmacology, 34(8), 857-863 (1995-08-01)
Depolarizations induced by a range of amino acids including some sulphur-containing excitatory transmitter candidates were evoked from motoneurones in the neonatal rat spinal cord under conditions that precluded activation of known ionotropic glutamate receptors. The responses could be partially and
Philipp Görtz et al.
Journal of the neurological sciences, 218(1-2), 109-114 (2004-02-05)
Severe hyperhomocysteinemia (50-200 microM) often presents itself with acute neuronal dysfunction including seizures and psychosis. Its moderate form (15-50 microM) is associated with cognitive impairment and dementia. We investigated the neuropharmacological effects of homocysteine and its oxidized forms, homocysteinesulfinic acid