H5000
己糖激酶 来源于酿酒酵母
Type III, lyophilized powder, ≥25 units/mg protein (biuret)
别名:
ATP:D-己糖-6-磷酸转移酶, 己糖激酶 来源于酵母
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关于此项目
化学文摘社编号:
UNSPSC Code:
12352204
eCl@ss:
32160410
EC Number:
232-611-5
MDL number:
Specific activity:
≥25 units/mg protein (biuret)
type
Type III
form
lyophilized powder
specific activity
≥25 units/mg protein (biuret)
mol wt
dimer 110 kDa
foreign activity
glucose-6-phosphate dehydrogenase and phosphoglucose isomerase ≤10%
storage temp.
−20°C
Gene Information
bakers yeast ... HXK1(850614), HXK2(852639)
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Biochem/physiol Actions
以ATP作为磷酸盐来源，催化C6位的 D-己糖的磷酸化。
不同的己糖具有不同的磷酸化速率（pH 7.5，30 °C）。
D-果糖 KM：0.33 mM
D-葡萄糖 KM：0.12 mM
D-甘露糖 KM：0.05 mM
酵母己糖激酶具有两种相似的亚型，即PI和PII（A和B）， 其等电点分别为5.25和4。
分子量： ~ 54 kDa (单体)
~110 kDa (二聚体)
最适pH：7.5至9.0
消光系数：在280 nm处，E1% = 8.85 (PI)和9.47 (PII)
活化剂：己糖激酶的活化需要 Mg2+ 离子（KM = 2.6 mM）。 己糖激酶可被儿茶酚胺及其相关化合物激活。
抑制剂：山梨糖-1-磷酸，多磷酸盐，6-脱氧-6-氟葡萄糖，2-C-羟基-甲基葡萄糖，木糖，来苏糖和硫醇反应性化合物（Hg2+ 和4-氯代苯甲酸酯）
不同的己糖具有不同的磷酸化速率（pH 7.5，30 °C）。
D-果糖 KM：0.33 mM
D-葡萄糖 KM：0.12 mM
D-甘露糖 KM：0.05 mM
酵母己糖激酶具有两种相似的亚型，即PI和PII（A和B）， 其等电点分别为5.25和4。
分子量： ~ 54 kDa (单体)
~110 kDa (二聚体)
最适pH：7.5至9.0
消光系数：在280 nm处，E1% = 8.85 (PI)和9.47 (PII)
活化剂：己糖激酶的活化需要 Mg2+ 离子（KM = 2.6 mM）。 己糖激酶可被儿茶酚胺及其相关化合物激活。
抑制剂：山梨糖-1-磷酸，多磷酸盐，6-脱氧-6-氟葡萄糖，2-C-羟基-甲基葡萄糖，木糖，来苏糖和硫醇反应性化合物（Hg2+ 和4-氯代苯甲酸酯）
Physical form
Lyophilized powder containing approx. 15% sodium citrate
Other Notes
One unit will phosphorylate 1.0 μmole of D-glucose per min at pH 7.6 at 25 °C, unless otherwise indicated below.
存储类别
11 - Combustible Solids
wgk
WGK 3
flash_point_f
Not applicable
flash_point_c
Not applicable
ppe
Eyeshields, Gloves, type N95 (US)
法规信息
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| 货号 | GTIN |
|---|---|
| H5000-250MG | 04061832924366 |
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