H7403
抗 组胺 兔抗
affinity isolated antibody, buffered aqueous solution
别名:
Anti Histamine Antibody, Histamine Antibody, Histamine Antibody - Anti-Histamine antibody produced in rabbit
biological source
rabbit
conjugate
unconjugated
antibody form
affinity isolated antibody
antibody product type
primary antibodies
clone
polyclonal
form
buffered aqueous solution
species reactivity
wide range
technique(s)
dot blot: 1:14,000 using histamine-BSA., immunohistochemistry: 1:100 using 4% paraformaldehyde/4% carbodiimide-fixed or 4% paraformaldehyde-fixed sections of rat stomach
shipped in
dry ice
storage temp.
−20°C
target post-translational modification
unmodified
Quality Level
General description
组胺（（2-（4-咪唑基）乙胺）是一种在周围组织中广泛分布的物质。组胺位于肠胃道的肥大细胞、神经元细胞和神经内分泌细胞中。它也在肺、肾、脑血管内皮细胞和整个周围神经系统中表达。
Immunogen
组胺与琥珀酰 KLH 结合
Application
兔源抗组胺抗体可用于：
- 免疫组化
- 测试土耳其拟鱥消化系统组织的免疫化学反应
- 免疫细胞化学检测
- 免疫荧光检测
Biochem/physiol Actions
组胺（2-（4-咪唑基）乙胺）介导各种生理活动，包括炎症、胃酸分泌和平滑肌收缩。它还涉及胚胎形成和肿瘤生长过程中细胞生长和分化的调节，以及有丝分裂原诱导的淋巴细胞增殖的抑制。在中枢神经系统（CNS）中，组胺是各种大脑活动的神经递质/神经调节剂。
该产品在多聚甲醛/碳二亚胺固定或多聚甲醛固定、石蜡包埋的大鼠胃切片（内分泌细胞和肥大细胞）中特异性染色含组胺的细胞。
Physical form
含有1% BSA及15 mM叠氮化钠的 0.01 M磷酸盐缓冲液（pH 7.4）溶液
Disclaimer
除非我们的产品目录或产品附带的其他公司文档另有说明，否则我们的产品仅供研究使用，不得用于任何其他目的，包括但不限于未经授权的商业用途、体外诊断用途、离体或体内治疗用途或任何类型的消费或应用于人类或动物。
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存储类别
10 - Combustible liquids
wgk
WGK 2
flash_point_f
Not applicable
flash_point_c
Not applicable
法规信息
低风险生物材料
常规特殊物品
此项目有
Jonathon L McClain et al.
Biomolecules, 13(11) (2023-11-25)
Histamine is a neuromodulator that affects gut motility and visceral sensitivity through intrinsic and extrinsic neural pathways, yet the mechanisms regulating histamine availability in these pathways remain poorly understood. Here, we show that enteric glia contribute to histamine clearance in
The role of histamine H4 receptor in immune and inflammatory disorders
Zampeli E, et al.
British Journal of Pharmacology, 157, 24-24 (2009)
Drew Stenesen et al.
eLife, 4, e10972-e10972 (2015-12-15)
Synaptic transmission from Drosophila photoreceptors to lamina neurons requires recycling of histamine neurotransmitter. Synaptic histamine is cleared by uptake into glia and conversion into carcinine, which functions as transport metabolite. How carcinine is transported from glia to photoreceptor neurons remains
Jasmin Becker et al.
Frontiers in physiology, 10, 329-329 (2019-04-12)
The density of intestinal mast cells has been reported to increase during inflammatory bowel disease (IBD). As mast cell mediators are known to increase the permeability of epithelial tight junctions, we hypothesized that antigen responses in sensitized animals might be
Immunohistochemical localization of cholecystokinin and histamine in gastrointestinal tract in flower fish
SENOL N, et al.
Experimental Physiology, 1(1), 26-34 (2006)
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