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Merck
CN

H8004

16α-羟雌酮

≥99% (HPLC)

别名:

1,3,5(10)-Estratriene-3,16α-diol-17-one, 16α-3,16-Dihydroxyestra-1,3,5(10)-trien-17-one

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关于此项目

经验公式(希尔记法):
C18H22O3
化学文摘社编号:
分子量:
286.37
UNSPSC Code:
12352200
PubChem Substance ID:
MDL number:
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InChI

1S/C18H22O3/c1-18-7-6-13-12-5-3-11(19)8-10(12)2-4-14(13)15(18)9-16(20)17(18)21/h3,5,8,13-16,19-20H,2,4,6-7,9H2,1H3/t13-,14-,15+,16+,18-/m0/s1

SMILES string

C[C@]12CC[C@H]3[C@@H](CCc4cc(O)ccc34)[C@@H]1C[C@@H](O)C2=O

InChI key

WPOCIZJTELRQMF-UJHHCITNSA-N

assay

≥99% (HPLC), ~95% (TLC)

pictograms

Health hazard

signalword

Danger

Hazard Classifications

Carc. 2 - Lact. - Repr. 1A

存储类别

6.1C - Combustible acute toxic Cat.3 / toxic compounds or compounds which causing chronic effects

wgk

WGK 1

flash_point_f

Not applicable

flash_point_c

Not applicable

法规信息

新产品
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历史批次信息供参考:

分析证书(COA)

Lot/Batch Number

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MaryFran R Sowers et al.
The Journal of nutrition, 136(6), 1588-1595 (2006-05-17)
Diet and lifestyle factors, body size, and smoking behavior may influence estrogen metabolism, but the nature of these relations may vary according to race/ethnic groups. We evaluated the association of lifestyle factors with estrogen metabolites 2-hydroxyestrone (2-OHE1) and 16alpha-hydroxyestrone (16alpha-OHE1)
G Maskarinec et al.
European journal of clinical nutrition, 66(9), 1044-1049 (2012-06-21)
Soy consumption may protect against breast cancer through modification of estrogen metabolism. We examined the effect of soy foods on urinary estrogens and the 2-hydroxy (OH)/16α-OH estrone (E(1)) ratio in two dietary interventions with premenopausal women. The Breast, Estrogens, And
Yukiko Morimoto et al.
Nutrition and cancer, 64(2), 307-314 (2012-02-02)
One of the hypothesized protective mechanisms of soy against breast cancer involves changes in estrogen metabolism to 2-hydroxy (OH) and 16α-OH estrogens. The current analysis examined the effect of soy foods on the 2:16α-OH E(1) ratio among premenopausal women during
Shawn Patel et al.
Nutrition (Burbank, Los Angeles County, Calif.), 27(7-8), 778-781 (2010-11-03)
We recently identified an inverse relation between systolic blood pressure (SBP) and serum 16α-hydroxyestrone, a metabolite of 17β-estradiol, in postmenopausal women. Formation of 16α-hydroxyestrone is catalyzed primarily by CYP1A2, a cytochrome P450 enzyme. The objective of this study was to
MaryFran R Sowers et al.
Arthritis and rheumatism, 54(8), 2481-2487 (2006-07-28)
To determine if levels of endogenous estrogen or estrogen metabolites are associated with an increased risk of developing knee osteoarthritis (OA) in women. Serum estradiol (E2) and 2 urinary estrogen metabolites (2-hydroxyestrone and 16alpha-hydroxyestrone) with radiographically defined prevalent and incident

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