跳转至内容
Merck
CN

H8034

HE-NECA

solid, ≥98% (HPLC)

别名:

2-(1-Hexyn-1-yl)adenosine-5′-N-ethyluronamide, 2-Hexynyl-5′-ethylcarboxamidoadenosine

登录 查看组织和合同定价。

选择尺寸

关于此项目

经验公式（希尔记法）:
C18H24N6O4 · xH2O
化学文摘社编号:
141018-30-6
分子量:
388.42 (anhydrous basis)
UNSPSC Code:
12352200
PubChem Substance ID:
24278473
MDL number:
MFCD03095611

主要文件

查看所有文档
技术服务
需要帮助？我们经验丰富的科学家团队随时乐意为您服务。
让我们为您提供帮助
技术服务
需要帮助？我们经验丰富的科学家团队随时乐意为您服务。
让我们为您提供帮助

assay

≥98% (HPLC)

form

solid

color

white

solubility

DMSO: >10 mg/mL, H2O: insoluble

storage temp.

2-8°C

SMILES string

CCCCC#Cc1nc(N)c2ncn([C@@H]3O[C@@H]([C@@H](O)[C@H]3O)C(=O)NCC)c2n1

InChI

1S/C18H24N6O4/c1-3-5-6-7-8-10-22-15(19)11-16(23-10)24(9-21-11)18-13(26)12(25)14(28-18)17(27)20-4-2/h9,12-14,18,25-26H,3-6H2,1-2H3,(H,20,27)(H2,19,22,23)/t12-,13+,14-,18+/m0/s1

InChI key

FDEACFAXFCKCHZ-MOROJQBDSA-N

Gene Information

human ... ADORA2A(135), ADORA2B(136)

Biochem/physiol Actions

A2 adenosine receptor agonist

存储类别

13 - Non Combustible Solids

wgk

WGK 3

flash_point_f

Not applicable

flash_point_c

Not applicable

ppe

Eyeshields, Gloves, type N95 (US)

法规信息

新产品

此项目有

历史批次信息供参考:

分析证书(COA)

Lot/Batch Number
100K4602
044K4611

没有发现合适的版本？

如果您需要特殊版本，可通过批号或批次号查找具体证书。

搜索COA

已有该产品？

在文件库中查找您最近购买产品的文档。

访问文档库

R Volpini et al.
Nucleosides & nucleotides, 18(11-12), 2511-2520 (2000-01-20)
The synthesis of 2-(hex-1-ynyl)adenosine derivatives substituted at the N6- and/or 5'-position was carried out on the basis that 2-(hex-1-ynyl)adenosine-5'-N-ethyluronamide (HENECA, 2) showed good affinity and different degree of selectivity for rat adenosine receptors. All new compounds were tested in radioligand
S Genovesi et al.
Journal of cardiovascular pharmacology, 35(2), 189-194 (2000-02-15)
The aim of this study was to investigate the effects of A1 and A2 adenosine-receptor activation on the sympathetic nervous system. The effects on efferent renal nerve activity of selective A1 (CCPA; 2-chloro-N-6-cyclopentyladenosine) and A2 (2HE-NECA; 2-hexynyl-5'-N-ethylcarboxamidoadenosine) adenosine-receptor agonists were
G Panzacchi et al.
Journal of hypertension, 15(12 Pt 2), 1785-1789 (1998-03-06)
To investigate the effects of the interaction between adenosine receptors and renal nerves on urinary sodium excretion and glomerular filtration rate. The effects on water and sodium excretion and glomerular filtration rate of A1 [2-chloro-N6-cyclopentyl-adenosine (CCPA)] and A2 [2-hesinyl-5'-N-ethyl-carboxamido-adenosine (2HE-NECA)]
R A Cunha et al.
British journal of pharmacology, 122(7), 1279-1284 (1998-01-08)
1. In the present study, we investigated the ability of a recently introduced non-xanthine A2A receptor antagonist, ZM241385 (4-(2-[7-amino-2-(2-furyl[1,2,4]-triazolo[2,3-a[1,3,5]triazin-5-yl -aminoethyl)phenol) to displace binding of the prototypical A2A adenosine receptor agonist [3H]CGS21680 (2-[4-(2-p-carboxyethyl)phenylamino]-5'-N-ethylcarboxamidoadenosine) and to modify the facilitatory responses caused by
G Protasoni et al.
Journal of hypertension, 13(12 Pt 2), 1753-1757 (1995-12-01)
To investigate the effects of the interaction between adenosine receptors and renal nerves on renin release. The effects on renin secretion of A1 (2-chloro-N6-cyclopentiladenosine) and A2 (2-hexynil-5'-N-ethyl-carboxamido-adenosine) adenosine-receptor agonists were studied in two groups of anaesthetized rats, each with one
查看所有相关文献

相关内容

我们的科学家团队拥有各种研究领域经验，包括生命科学、材料科学、化学合成、色谱、分析及许多其他领域.

联系客户支持