H9762
Haptoglobin Human, Phenotype 2-2
98-100%, essentially salt-free, lyophilized powder
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Form:
essentially salt-free, lyophilized powder
Assay:
98-100%
Biological source:
human
General description
Haptoglobin is an α2-globulin found in normal plasma at a concentration of 82-236 mg/dl and accounts for 0.4-2.6% of the total plasma proteins. . The monomeric form of this acute phase plasma protein is composed of four polypeptide chains: two α chains and two β chains.
Haptoglobin is an acute phase protein that scavenges hemoglobin released into the circulation. Haptoglobin, the plasma protein with highest binding affinity to hemoglobin, is mainly expressed in the liver.
Application
Haptoglobin was used to study haptoglobin expression and release by rabbit oviduct and endometrium. It was also used to analyze its localization in blastocyst extra-embryonic matrix and fluid during pre-implantation.
Other Notes
Occurs as 3 major phenotypes: type 1-1, type 2-1, type 2-2.
存储类别
11 - Combustible Solids
wgk
WGK 3
flash_point_f
Not applicable
flash_point_c
Not applicable
法规信息
高风险级别生物产品--人源产品
此项目有
A Herrler et al.
Human reproduction (Oxford, England), 19(12), 2730-2737 (2004-09-25)
Evidence is emerging that haptoglobin, an acute phase protein with immunomodulatory properties, is expressed by the endometrium of various species. The present study describes an in-depth investigation of haptoglobin expression and release in the rabbit reproductive tract and in preimplantation
Hanne Van Gorp et al.
The Journal of general virology, 89(Pt 12), 2943-2953 (2008-11-15)
The porcine reproductive and respiratory syndrome virus (PRRSV) shows a restricted tropism for subsets of porcine macrophages in vivo. To date, two PRRSV receptors have been identified on primary macrophages, heparan sulphate for binding and sialoadhesin for binding and internalization.
C Gerbert et al.
Journal of dairy science, 101(8), 7348-7360 (2018-05-21)
Animal welfare in dairy calf husbandry depends on calf rearing and is probably improved by intensive milk feeding programs. In addition, butyrate supplementation in milk replacer (MR) stimulates postnatal growth and may affect the immune system in calves. We have