H9790
Anti-HOXA5 antibody produced in rabbit
~1.0 mg/mL, affinity isolated antibody, buffered aqueous solution
别名:
Anti-HOX1, Anti-HOX1.3, Anti-HOX1C, Anti-Homeo box 1C, Anti-Homeo box A5
biological source
rabbit
conjugate
unconjugated
antibody form
affinity isolated antibody
antibody product type
primary antibodies
clone
polyclonal
form
buffered aqueous solution
mol wt
antigen ~40 kDa
species reactivity
human
concentration
~1.0 mg/mL
technique(s)
western blot: 0.5-1 μg/mL using using lysates of HEK-293T cells over-expressing human HOXA5
UniProt accession no.
shipped in
dry ice
storage temp.
−20°C
target post-translational modification
unmodified
Gene Information
human ... HOXA5(3202)
mouse ... Hoxa5(15402)
rat ... Hoxa5(79241)
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General description
Homeobox A5 (HOXA5) is mapped to human chromosome 7p15.2. It belongs to amino acid Antennapedia (Antp) -class homeodomain proteins.
Application
Anti-HOXA5 antibody produced in rabbit has been used in immunoblotting.
Biochem/physiol Actions
Homeobox A5 (HOXA5) mediates organogenesis and development of mammary glands, lungs, digestive tract and thyroid. It is essential for ovary homeostasis. Mutation in HOXA5 gene hampers organogenesis as it affects axial specification in the cervico-thoracic level. HOXA5 has been shown to play an important role in breast tumorigenesis. It also regulates hematopoiesis by interacting with pleiotrophin (PTN).
Physical form
Solution in 0.01 M phosphate buffered saline, pH 7.4, containing 15 mM sodium azide.
Disclaimer
Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.
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存储类别
10 - Combustible liquids
flash_point_f
Not applicable
flash_point_c
Not applicable
ppe
Eyeshields, Gloves, multi-purpose combination respirator cartridge (US)
法规信息
新产品
此项目有
Effect of silencing HOXA5 gene expression using RNA interference on cell cycle and apoptosis in Jurkat cells
Huang HP, et al.
International Journal of Molecular Medicine, 37(3), 669-678 (2016)
Identification of transcriptional targets of HOXA5
Chen H, et al.
The Journal of Biological Chemistry, 280(19), 19373-19380 (2005)
Hoxa5: a key player in development and disease
Jeannotte L, et al.
Journal of developmental biology, 4(2), 13-13 (2016)
HOXA5-Mediated Stabilization of II?BI? Inhibits the NF-I?B Pathway and Suppresses Malignant Transformation of Breast Epithelial Cells.
Pai, et al.
Cancer research, 82, 3802-3814 (2023)
Compromised HOXA5 function can limit p53 expression in human breast tumours
Raman V, et al.
Nature, 405(6789), 974-974 (2000)
相关内容
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