Anti-HOXB6 (C-terminal) antibody produced in rabbit

Homeobox 6 (HOXB6) protein is expressed in human hematopoietic progenitor cells (HPCs). The HOXB6 gene is mapped on the human chromosome at 17q21.32.

synthetic peptide corresponding to amino acids 108-122 of human HOXB6 conjugated to KLH. The corresponding sequence is identical in mouse.

Anti-HOXB6 (C-terminal) antibody produced in rabbit may be used in immunoblotting.

Anti-HOXB6 (C-terminal) recognizes human HOXB6 (also known as HOX2B, HU-2 and Hox-2.

Homeobox 6 (HOXB6) is frequently overexpressed in human acute myeloid leukemia (AML). HOXB6 gene overexpression extended hematopoietic stem cells (HSCs) and myeloid precursors while decreasing erythropoiesis and lymphopoiesis.

Solution in 0.01 M phosphate buffered saline, pH 7.4, containing 15 mM sodium azide.

For continuous use, store at 2-8 °C for up to one month. For extended storage, freeze in working aliquots at –20 °C. Repeated freezing and thawing, or storage in “frost-free” freezers, is not recommended. If slight turbidity occurs upon prolonged storage, clarify the solution by centrifugation before use. Working dilutions should be discarded if not used within 12 hours.

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