HPA043135
Anti-TET2 antibody produced in rabbit
Prestige Antibodies® Powered by Atlas Antibodies, affinity isolated antibody, buffered aqueous glycerol solution
别名:
Anti-Flj20032, Anti-Kiaa1546, Anti-Tet oncogene family member 2
biological source
rabbit
conjugate
unconjugated
antibody form
affinity isolated antibody
clone
polyclonal
product line
Prestige Antibodies® Powered by Atlas Antibodies
form
buffered aqueous glycerol solution
species reactivity
human
technique(s)
immunohistochemistry (formalin-fixed, paraffin-embedded sections): suitable
immunogen sequence
KTTSHINAINSQATNELSCEITHPSHTSGQINSAQTSNSELPPKPAAVVSEACDADDADNASKLAAMLNTCSFQKPEQLQQQKSVFEICPSPAENNIQGTTKLASGE
shipped in
wet ice
storage temp.
−20°C
Gene Information
human ... TET2(54790)
General description
Rabbit polyclonal anti-TET2 antibody recognizes human Tet oncogene family member 2/Ten-Eleven-Translocation 2.
Tet oncogene family member 2/Ten-Eleven-Translocation 2 (TET2) is an α-ketoglutarate and Fe2+-dependent enzyme that alters the epigenetic status of DNA by oxidizing 5-methylcytosine to 5-hydroxymethylcytosine (5hmC). TET2 negatively regulates the homeostasis and differentiation of hematopoietic stem cells. Dysfunction of TET2 is associated with myeloproliferative neoplasms.
Immunogen
tet oncogene family member 2 recombinant protein epitope signature tag (PrEST)
Application
Rabbit polyclonal anti-TET2 antibody is used to tag Tet oncogene family member 2/Ten-Eleven-Translocation 2 for detection and quantitation by immunocytochemical and immunohistochemical (IHC) techniques such as immunoblotting, immunoprecipitation, and immunofluorescence. It is used as a probe to determine the presence and roles of Tet oncogene family member 2/Ten-Eleven-Translocation 2 in the epigenetic regulation of hematopoietic cell differention and proliferation.
Features and Benefits
Prestige Antibodies® are highly characterized and extensively validated antibodies with the added benefit of all available characterization data for each target being accessible via the Human Protein Atlas portal linked just below the product name at the top of this page. The uniqueness and low cross-reactivity of the Prestige Antibodies® to other proteins are due to a thorough selection of antigen regions, affinity purification, and stringent selection. Prestige antigen controls are available for every corresponding Prestige Antibody and can be found in the linkage section.
Every Prestige Antibody is tested in the following ways:
Every Prestige Antibody is tested in the following ways:
- IHC tissue array of 44 normal human tissues and 20 of the most common cancer type tissues.
- Protein array of 364 human recombinant protein fragments.
Physical form
Solution in phosphate buffered saline, pH 7.2, containing 40% glycerol and 0.02% sodium azide.
Legal Information
Prestige Antibodies is a registered trademark of Merck KGaA, Darmstadt, Germany
存储类别
12 - Non Combustible Liquids
wgk
WGK 1
flash_point_f
Not applicable
flash_point_c
Not applicable
法规信息
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