description
Functional Validation of miRNA Gene Targets
product line
MISSION®
concentration
≥1x105 VP/ml (via p24 assay)
human 3′UTR sequence
TCTGAAGAAAAGACAAATGAAGCCTAATCGTTTTTCTAGAAGGAAAATAAATTCTAATTGATAATGAATTTCGTTCAATATTATCCTTGCTTTTCATGGAAACACAGTAACCTGTATGCTGTGATTCCTGTTCACTACTGTGTAAAGTAAAAACTAAAAAAATACAAAATACAAAacacacacacacacacacacacacacacacacacacacacaAAATAAATCCGGGTGTGCCTGAACCTCAGACCTAGTAAT (3′UTR sequences are truncated after the first 255 bases)
NCBI accession no.
shipped in
dry ice
storage temp.
−70°C
Gene Information
human ... ZEB1(6935)
Application
To see more application data, protocols, and vector maps visit www.sigma.com/3utr.
Physical form
200 μL of at least 105 VP/mL (via p24 titering assay) lentiviral particles are provided as frozen stock.
Legal Information
SwitchGear Genomics is a trademark of SwitchGear Genomics
Use of this product is subject to one or more license agreements. For details, please see www.sigmaaldrich.com/missionlicense.
GoClone is a trademark of SwitchGear Genomics
MISSION is a registered trademark of Merck KGaA, Darmstadt, Germany
存储类别
12 - Non Combustible Liquids
wgk
WGK 3
flash_point_f
Not applicable
flash_point_c
Not applicable
法规信息
新产品
此项目有
Shichang Deng et al.
Oncotarget, 6(37), 39661-39675 (2015-10-27)
Recent evidences suggest that the acidic microenvironment might facilitate epithelial mesenchymal transition (EMT) of tumor cells, while the effects of acidity on EMT of pancreatic cancer (PC) remain undefined. The present study demonstrated that acidity suppressed miR-652 expression, which further
Hengyuan Pang et al.
Biochemical and biophysical research communications, 468(4), 739-745 (2015-11-12)
Invasion and migration of glioblastoma multiforme (GBM) is a multistep process and an important phenotype that causes this disease to invade surrounding tissues in the brain. The purpose of this study was to determine the role of miR-590-3p in regulation
Gongcai Qiu et al.
Biochemical and biophysical research communications, 463(3), 315-321 (2015-05-30)
Hepatocellular carcinoma (HCC) is the third most common cause of cancer deaths worldwide. miRNAs have been suggested to have important roles in HCC development. The purpose of this study was to determine the role of miR-139-5p in regulation of epithelial-mesenchymal
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