I123
ICI 216,140
>95%, solid
别名:
(CH3)2CHCO-His-Trp-Ala-Val-D-Ala-His-Leu-NHCH3
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关于此项目
assay
>95%
form
solid
color
white
storage temp.
−20°C
SMILES string
CNC(=O)[C@H](CC(C)C)NC(=O)[C@H](Cc1c[nH]cn1)NC(=O)[C@@H](C)NC(=O)[C@@H](NC(=O)[C@H](C)NC(=O)[C@H](Cc2c[nH]c3ccccc23)NC(=O)[C@H](Cc4c[nH]cn4)NC(=O)C(C)C)C(C)C
Biochem/physiol Actions
Potent in vivo receptor antagonist of the bombesin/gastrin releasing peptide receptor.
存储类别
13 - Non Combustible Solids
wgk
WGK 3
flash_point_f
Not applicable
flash_point_c
Not applicable
ppe
Eyeshields, Gloves, type N95 (US)
法规信息
新产品
此项目有
B J Campbell et al.
Regulatory peptides, 49(3), 249-255 (1994-01-13)
The mechanisms of action of gastrin and gastrin releasing peptide (GRP) in stimulating gastric acid secretion were examined in the anaesthetized turkey. Gastrin and GRP produced dose-dependent increases in acid secretion that were inhibited by the gastrin/CCK-B antagonist CI988. The
B Campbell et al.
The American journal of physiology, 261(1 Pt 1), G16-G21 (1991-07-01)
Endocrine cells in the acid-secreting part of the avian stomach, the proventriculus, contain two forms of gastrin-releasing peptide (GRP) of 27 and 6 residues, respectively. We have examined the actions of exogenous GRP-27 and GRP-6 and endogenously released GRP in
Gang Ren et al.
Journal of nuclear medicine : official publication, Society of Nuclear Medicine, 50(10), 1692-1699 (2009-09-18)
Dialkylamino-alkyl-benzamides possess an affinity for melanin, suggesting that labeling of such benzamides with (18)F could potentially produce melanin-targeted PET probes able to identify melanotic melanoma metastases in vivo with high sensitivity and specificity. In this study, N-[2-(diethylamino)ethyl]-4-(18)F-fluorobenzamide ((18)F-FBZA) was synthesized