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Merck
CN

I3653

Anti-Interferon β antibody produced in goat

affinity isolated antibody, lyophilized powder

别名:

Anti-IFN-β

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关于此项目

UNSPSC Code:
51111800
NACRES:
NA.41
MDL number:
Conjugate:
unconjugated
Clone:
polyclonal
Application:
WB
Citations:
1
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biological source

goat

conjugate

unconjugated

antibody form

affinity isolated antibody

antibody product type

primary antibodies

clone

polyclonal

form

lyophilized powder

species reactivity

human

technique(s)

western blot: 0.1-2.0 μg/mL

UniProt accession no.

storage temp.

−20°C

target post-translational modification

unmodified

Quality Level

Gene Information

human ... IFNB1(3456)

General description

Type I interferons are proteins produced in response to inducers like viral infection and can be divided into α and β subtypes. IFN-β provokes high antiproliferation response in certain cells like embryonal carcinoma, melanoma and melanocytes. It also has high potency in treatment of multiple sclerosis and certain cancers. Anti-interferon β antibody can be used in western blot. Goat anti-interferon β antibody reacts specifically with human interferon-β and has shown no cross reactivity with recombinant human interferon-γ.

Immunogen

recombinant human IFN-β, expressed in Escherichia coli.

Application

Anti-interferon β antibody can be used in immunoblotting. It can also be used to neutralize the bioactivity of recombinant human interferon-β.

Biochem/physiol Actions

The antibody will neutralize the biological activity of recombinant human IFN-β. It will not block the biological activity of recombinant human IFN-α or IFN-γ.

Physical form

Lyophilized from a solution in phosphate buffered saline containing carbohydrates.

Disclaimer

Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.

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存储类别

11 - Combustible Solids

wgk

WGK 3

flash_point_f

Not applicable

flash_point_c

Not applicable

法规信息

低风险生物材料
常规特殊物品
此项目有

历史批次信息供参考:

分析证书(COA)

Lot/Batch Number

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P Belhumeur et al.
Molecular and cellular biology, 13(5), 2846-2857 (1993-05-01)
In the current study, we have addressed the role of interferons (IFNs) in controlling the differentiation of pluripotent P19 embryonal carcinoma (EC) cells. Blocking IFN activity in the culture medium of differentiating cells with antibodies leads to a strong decrease

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