I5125
肌醇 -肌醇
≥99% (GC), powder, precursor of membrane phospho-inositides and phospholipid
别名:
meso-肌醇, 环己六醇, 肌糖
一般描述
肌醇（MI，myo-肌醇）是一种糖样分子，主要存在于人脑的神经胶质细胞中。它是C6糖醇的立体异构体，属于肌醇家族的一员。可作为三磷酸肌醇的前体，也可充当胞内第二信使。Myo-肌醇调节多种激素水平，如促甲状腺激素、促卵泡激素(FSH)和胰岛素。Myo-肌醇和d-chiro-肌醇（肌醇的另一种立体异构体）以不同方式平衡胰岛素抵抗(IR)有关的代谢异常。
应用
肌醇已用于：
- 作为气-液相色谱法（GC）单糖分析的标准品
- 作为无R海马培养基的组成部分，用于腹腔巨噬细胞（PMΦ）的培养，以研究细胞糖酵解代谢
- 作为SOFaaci培养基的补充，用于延长体外胚胎生长
- 作为α最低必需培养基（αMEM）完全培养基的组分，用于培养自然杀伤（NK）细胞系
生化/生理作用
肌醇（MI）作为渗透剂，是膜磷酸肌醇和磷脂的重要前体。它有助于形成细胞膜和髓鞘片结构。在阿尔茨海默症、脑胶质瘤病和脑肿瘤等各种脑部疾病中观察到肌醇（MI）浓度增加。
膜磷脂、糖基化磷脂酰肌醇锚定蛋白、磷酸肌醇酯第二信使的成分,其中锚定蛋白可将糖蛋白锚定到细胞膜上。
储存分类代码
11 - Combustible Solids
WGK
WGK 3
闪点(°F)
Not applicable
闪点(°C)
Not applicable
个人防护装备
Eyeshields, Gloves, type N95 (US)
历史批次信息供参考:
分析证书(COA)
Lot/Batch Number
Hugo A Méndez-Hernández et al.
Plants (Basel, Switzerland), 10(10) (2021-10-24)
Auxin plays a central role in growth and plant development. To maintain auxin homeostasis, biological processes such as biosynthesis, transport, degradation, and reversible conjugation are essential. The Gretchen Hagen 3 (GH3) family genes codify for the enzymes that esterify indole-3-acetic
Hiroki Okada et al.
STAR protocols, 2(3), 100733-100733 (2021-08-31)
Microscopy-based analysis of protein accumulation at a given subcellular location in real time provides invaluable insights into the function of a protein in a specific process. Here, we describe a detailed protocol for determining protein accumulation kinetics at the division
For Yue Tso et al.
PloS one, 16(3), e0247640-e0247640 (2021-03-05)
Neutralizing-antibody (nAb) is the major focus of most ongoing COVID-19 vaccine trials. However, nAb response against SARS-CoV-2, when present, decays rapidly. Given the myriad roles of antibodies in immune responses, it is possible that antibodies could also mediate protection against
Satu Hänninen et al.
Bio-protocol, 7(9), e2268-e2268 (2017-05-05)
Glycerophospholipids consist of a glycerophosphate backbone to which are esterified two acyl chains and a polar head group. The head group (e.g., choline, ethanolamine, serine or inositol) defines the glycerophospholipid class, while the acyl chains together with the head group
Mark A Gillespie et al.
STAR protocols, 1(3), 100216-100216 (2020-12-31)
Quantitative changes in transcription factor (TF) abundance regulate dynamic cellular processes, including cell fate decisions. Protein copy number provides information about the relative stoichiometry of TFs that can be used to determine how quantitative changes in TF abundance influence gene
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