I6005
myo-Inositol hexasulfate hexapotassium salt
别名:
Inositol hexakissulfate, InsS6
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关于此项目
线性分子式:
C6H6O24S6K6
化学文摘社编号:
分子量:
889.08
UNSPSC Code:
12352201
PubChem Substance ID:
MDL number:
InChI
1S/C6H12O24S6.K.H/c7-31(8,9)25-1-2(26-32(10,11)12)4(28-34(16,17)18)6(30-36(22,23)24)5(29-35(19,20)21)3(1)27-33(13,14)15;;/h1-6H,(H,7,8,9)(H,10,11,12)(H,13,14,15)(H,16,17,18)(H,19,20,21)(H,22,23,24);;
SMILES string
[K].OS(=O)(=O)OC1C(OS(O)(=O)=O)C(OS(O)(=O)=O)C(OS(O)(=O)=O)C(OS(O)(=O)=O)C1OS(O)(=O)=O
InChI key
JYVHCOUFXHFSLT-UHFFFAOYSA-N
storage temp.
−20°C
Biochem/physiol Actions
InsS6 has a molecular footprint and negative surface charge that is similar to that of phytic acid (InsP6), but with lower biological activity. It is used as a control in studies of the cellular actions of phytic acid. It is also a competitive inhibitor of Aspergillus phytase.
存储类别
11 - Combustible Solids
wgk
WGK 3
flash_point_f
Not applicable
flash_point_c
Not applicable
ppe
Eyeshields, Gloves, type N95 (US)
法规信息
新产品
此项目有
N M Dean et al.
The Biochemical journal, 250(2), 493-500 (1988-03-01)
Previous studies demonstrated a multiplicity of isomers of inositol phosphates in GH3 rat pituitary tumour cells. In order to determine their origin, we have investigated the metabolism of radiolabelled inositol phosphates (IPn) in GH3 cell homogenates by using h.p.l.c. I(1,4,5)P3
G Oshima
Thrombosis research, 58(3), 243-250 (1990-05-01)
Thrombin-clotting time of fibrinogen was delayed by inositol hexasulfate (IHS). Clotting time of the recalcified plasma was also delayed by IHS. Moreover, when IHS was intravenously injected into anesthetized male rabbits (0.11 mmoles/kg), it delayed clotting time of the recalcified
R Kojima et al.
Japanese journal of pharmacology, 53(3), 347-358 (1990-07-01)
We examined the protective effect of inositol hexasulfate (IS6) against tobramycin (TOB)-induced nephrotoxicity. In the electrophoretic analysis, TOB alone and IS6 alone were observed as single spots on the cathode and anode sides, respectively. However, in the mixture of TOB
Sonali P Jog et al.
Archives of biochemistry and biophysics, 440(2), 133-140 (2005-07-30)
Phytases catalyze the hydrolysis of phytic acid (InsP6, myo-inositol hexakisphosphate), the most abundant inositol phosphate in cells. In cereal grains and legumes, it constitutes 3-5% of the dry weight of seeds. The inability of humans and monogastric animals such as
M Guzmán-Casado et al.
International journal of biological macromolecules, 28(4), 305-313 (2001-04-20)
The interaction of an amino-terminal-truncated 139 amino-acids form of human acidic fibroblast growth factor with myo-inositol hexasulphate and low molecular weight (3500 g mol(-1)) heparin has been studied by isothermal titration calorimetry, differential scanning calorimetry and Fourier transform infrared spectroscopy.
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