I7006
双(3-氨基丙基)胺
别名:
3,3′-二氨基二丙胺, 3,3′-亚氨基二丙胺, N-(3-氨丙基)-1,3-丙二胺, 二亚丙基三胺, 去甲精眯
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关于此项目
线性分子式:
(NH2CH2CH2CH2)2NH
化学文摘社编号:
分子量:
131.22
EC Number:
200-261-2
UNSPSC Code:
12352100
PubChem Substance ID:
Beilstein/REAXYS Number:
1071254
MDL number:
refractive index
n20/D 1.481 (lit.)
bp
151 °C/50 mmHg (lit.)
mp
−14 °C (lit.)
density
0.938 g/mL at 25 °C (lit.)
storage temp.
2-8°C
SMILES string
NCCCNCCCN
InChI
1S/C6H17N3/c7-3-1-5-9-6-2-4-8/h9H,1-8H2
InChI key
OTBHHUPVCYLGQO-UHFFFAOYSA-N
Gene Information
mouse ... Odc1(18263)
signalword
Danger
Hazard Classifications
Acute Tox. 1 Inhalation - Acute Tox. 3 Dermal - Acute Tox. 4 Oral - Muta. 2 - Skin Corr. 1A - Skin Sens. 1A - STOT RE 2
target_organs
thymus
存储类别
6.1B - Non-combustible acute toxic Cat. 1 and 2 / very toxic hazardous materials
wgk
WGK 2
flash_point_f
242.6 °F - closed cup
flash_point_c
117 °C - closed cup
ppe
Faceshields, Gloves, Goggles, type ABEK (EN14387) respirator filter
法规信息
新产品
此项目有
H Nakao et al.
Journal of general microbiology, 135(Pt 2), 345-351 (1989-02-01)
Previous investigations have shown that members of the genus Vibrio possess a novel enzyme activity decarboxylating L-2,4-diaminobutyric acid (DABA) to 1,3-diaminopropane (DAP). In this paper we describe the purification, by about 3600-fold, of the enzyme from V. alginolyticus. The purified
N J Prakash et al.
Anticancer research, 8(4), 563-568 (1988-07-01)
The structural specificities of the natural polyamines putrescine (Put), spermidine (Spd) and spermine (Spm) for cell growth are rather stringent, suggesting that appropriate structural analogues of these polycations could serve as potential antineoplastic agents via polyamine antagonism. Norspermidine (Nspd), a
Santiago Alejandro et al.
The EMBO journal, 26(13), 3203-3215 (2007-06-15)
A genetic screen of Arabidopsis 'activation-tagging' mutant collection based on tolerance to norspermidine resulted in a dominant mutant (par1-1D) with increased expression of the QSO2 gene (At1g15020), encoding a member of the quiescin-sulfhydryl oxidase (QSO) family. The par1-1D mutant and
Johannes Ghatnekar et al.
Bioorganic & medicinal chemistry, 15(23), 7426-7433 (2007-09-18)
We here report the synthesis of the two polyamine-based nucleoside derivatives 5-{[bis-(3-aminopropyl)amino]acetamido-1-propynyl}uridine and 2-{[bis-(3-aminopropyl)amino]-acetamido-1-propynyl}adenosine. The various polyamine derivatives have been used in thermal melting analysis using DNA from herring testes, and in cellular studies using four different cell lines. The
T Shinki et al.
European journal of biochemistry, 183(2), 285-290 (1989-08-01)
We have reported that spermidine N1-acetyltransferase has a larger role than ornithine decarboxylase in putrescine synthesis in chick duodenum induced by 1 alpha,25-dihydroxycholecalciferol (calcitriol) [Shinki, T., Kadofuku, T., Sato, T. and Suda, T. (1986) J. Biol. Chem. 261, 11712-11716]. In
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