I7146
Ilimaquinone
别名:
3-[(Decahydro-1β,2β,4aβ-trimethyl-5-methylene-1-naphthyl)methyl]-2-hydroxy-5-methoxybenzoquinone
储存温度
−20°C
SMILES字符串
[H][C@@]12CCCC(=C)[C@@]1(C)CC[C@H](C)[C@@]2(C)CC3=C(O)C(=O)C=C(OC)C3=O
生化/生理作用
Induces reversible breakdown of Golgi membranes.
储存分类代码
13 - Non Combustible Solids
WGK
WGK 3
闪点(°F)
Not applicable
闪点(°C)
Not applicable
个人防护装备
Eyeshields, Gloves, type N95 (US)
法规信息
新产品
此项目有
H J Wang et al.
Journal of cell science, 110 ( Pt 24), 3043-3053 (1998-02-21)
Autocrine motility factor receptor (AMF-R) is a marker for a distinct smooth membranous tubule. Ilimaquinone (IQ) is a sea sponge metabolite which induces the complete vesiculation of the Golgi apparatus and we show here that the addition of IQ to
E Goclik et al.
Journal of natural products, 63(8), 1150-1152 (2000-09-09)
From the dichloromethane solubles of the tropical marine sponge Dactylospongia elegans, a new aromatic substituted sesquiterpene, pelorol (1), and the known sesquiterpene, ilimaquinone (2), were isolated. The structures of 1 and 2 were deduced from their spectroscopic data. The biological
H R Rangel et al.
Cell biology international, 21(6), 337-339 (1997-06-01)
Illimaquinone, a sponge metabolite that disrupts the Golgi complex in mammalian cells, stopped proliferation and induced morphological and ultrastructural changes in promastigotes of L. mexicana. Radioactive labeling of proteins demonstrates an increased excretion function and diminution of membrane acid phosphatase
H S Radeke et al.
Bioorganic & medicinal chemistry, 6(8), 1227-1232 (1998-10-24)
The marine sponge metabolite ilimaquinone (1) displays a broad range of biological activities. To better understand the effects of this natural product, a photoaffinity analogue was synthesized and used to probe the cellular interactions of ilimaquinone. Irradiation of photoaffinity probe
S Loya et al.
Antimicrobial agents and chemotherapy, 34(10), 2009-2012 (1990-10-01)
We studied the effect of the natural marine substance illimaquinone on the catalytic activities of reverse transcriptase from human immunodeficiency virus type 1. Illimaquinone inhibited the RNase H activity of the enzyme at concentrations of 5 to 10 microgram/ml, whereas
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