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Merck
CN

I7146

Ilimaquinone

别名:

3-[(Decahydro-1β,2β,4aβ-trimethyl-5-methylene-1-naphthyl)methyl]-2-hydroxy-5-methoxybenzoquinone

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关于此项目

经验公式(希尔记法):
C22H30O4
化学文摘社编号:
分子量:
358.47
UNSPSC Code:
12352200
PubChem Substance ID:
MDL number:
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storage temp.

−20°C

SMILES string

[H][C@@]12CCCC(=C)[C@@]1(C)CC[C@H](C)[C@@]2(C)CC3=C(O)C(=O)C=C(OC)C3=O

Biochem/physiol Actions

Induces reversible breakdown of Golgi membranes.


存储类别

13 - Non Combustible Solids

wgk

WGK 3

flash_point_f

Not applicable

flash_point_c

Not applicable

ppe

Eyeshields, Gloves, type N95 (US)

法规信息

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历史批次信息供参考:

分析证书(COA)

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B Veit et al.
The Journal of cell biology, 122(6), 1197-1206 (1993-09-01)
We have recently shown that ilimaquinone (IQ) causes the breakdown of Golgi membranes into small vesicles (VGMs for vesiculated Golgi membranes) and inhibits vesicular protein transport between successive Golgi cisternae (Takizawa et al., 1993). While other intracellular organelles, intermediate filaments
Keeping Golgi membranes intact in the pericentriolar region of mammalian cells.
U Acharya et al.
Biochemical Society transactions, 23(3), 538-541 (1995-08-01)
T C Taylor et al.
Molecular biology of the cell, 5(2), 237-252 (1994-02-01)
We investigated the role of ADP-ribosylation factors (ARFs) in Golgi function using biochemical and morphological cell-free assays. An ARF-free cytosol produced from soluble Chinese hamster ovary (CHO) extracts supports intra-Golgi transport by a mechanism that is biochemically indistinguishable from control