I7146
Ilimaquinone
别名:
3-[(Decahydro-1β,2β,4aβ-trimethyl-5-methylene-1-naphthyl)methyl]-2-hydroxy-5-methoxybenzoquinone
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关于此项目
经验公式（希尔记法）:
C22H30O4
化学文摘社编号:
分子量:
358.47
UNSPSC Code:
12352200
PubChem Substance ID:
MDL number:
SMILES string
[H][C@@]12CCCC(=C)[C@@]1(C)CC[C@H](C)[C@@]2(C)CC3=C(O)C(=O)C=C(OC)C3=O
storage temp.
−20°C
Biochem/physiol Actions
Induces reversible breakdown of Golgi membranes.
存储类别
13 - Non Combustible Solids
wgk
WGK 3
flash_point_f
Not applicable
flash_point_c
Not applicable
ppe
Eyeshields, Gloves, type N95 (US)
法规信息
新产品
此项目有
C Poüs et al.
The Journal of cell biology, 142(1), 153-165 (1998-07-14)
We found that the magnesium salt of ilimaquinone, named 201-F, specifically disassembled dynamically unstable microtubules in fibroblasts and various epithelial cell lines. Unlike classical tubulin- interacting drugs such as nocodazole or colchicine which affect all classes of microtubules, 201-F did
E Goclik et al.
Journal of natural products, 63(8), 1150-1152 (2000-09-09)
From the dichloromethane solubles of the tropical marine sponge Dactylospongia elegans, a new aromatic substituted sesquiterpene, pelorol (1), and the known sesquiterpene, ilimaquinone (2), were isolated. The structures of 1 and 2 were deduced from their spectroscopic data. The biological
S Loya et al.
The Journal of biological chemistry, 268(13), 9323-9328 (1993-05-05)
Illimaquinone, a natural marine product, was shown by us to inhibit preferentially the ribonuclease H (RNase H) activity of the reverse transcriptase (RT) of human immunodeficiency virus type 1 (HIV-1). We have also shown that illimaquinone inhibits the RNase H
H J Wang et al.
Journal of cell science, 110 ( Pt 24), 3043-3053 (1998-02-21)
Autocrine motility factor receptor (AMF-R) is a marker for a distinct smooth membranous tubule. Ilimaquinone (IQ) is a sea sponge metabolite which induces the complete vesiculation of the Golgi apparatus and we show here that the addition of IQ to
H S Radeke et al.
Bioorganic & medicinal chemistry, 6(8), 1227-1232 (1998-10-24)
The marine sponge metabolite ilimaquinone (1) displays a broad range of biological activities. To better understand the effects of this natural product, a photoaffinity analogue was synthesized and used to probe the cellular interactions of ilimaquinone. Irradiation of photoaffinity probe
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