I7388
异黄蝶呤
≥97.5%, powder
别名:
2-氨基-4,7-二羟基-1,3,5,8-四氮杂萘, 2-氨基-4,7-二羟基蝶啶, 2-氨基-4,7-蝶啶二醇
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关于此项目
经验公式（希尔记法）:
C6H5N5O2
化学文摘社编号:
分子量:
179.14
UNSPSC Code:
41106305
NACRES:
NA.51
PubChem Substance ID:
EC Number:
208-469-5
Beilstein/REAXYS Number:
181594
MDL number:
assay
≥97.5%
form
powder
color
off-white
solubility
1 M NaOH: 50 mg/mL, clear, very dark yellow
storage temp.
room temp
SMILES string
NC1=NC2=C(N=CC(=O)N2)C(=O)N1
InChI
1S/C6H5N5O2/c7-6-10-4-3(5(13)11-6)8-1-2(12)9-4/h1H,(H4,7,9,10,11,12,13)
InChI key
GLKCOBIIZKYKFN-UHFFFAOYSA-N
Application
Isoxanthopterin is a substrate for the enzyme isoxanthopterin deaminase.
Other Notes
Product of xanthine oxidase oxidation of pterin, an enzyme involved in reactive oxygen formation.
存储类别
13 - Non Combustible Solids
wgk
WGK 3
flash_point_f
Not applicable
flash_point_c
Not applicable
ppe
Eyeshields, Gloves, type N95 (US)
R Walter et al.
American journal of respiratory and critical care medicine, 156(6), 2006-2010 (1997-12-31)
Pulmonary endothelial dysfunction is the hallmark of acute lung injury. Impaired pulmonary endothelial nitric oxide (NO) production in this event has been described. Tetrahydrobiopterin (BH4) is an essential cofactor for NO synthase and modulator of its activity. At high local
Burki Rajendar et al.
Bioorganic & medicinal chemistry, 17(1), 351-359 (2008-11-18)
Isoxanthopterin (IX) has two edges with hydrogen bond-forming sites suitable for binding to thymine (T) and cytosine (C). The binding affinity of IX for T or C is stronger than for adenine (A) and guanine (G), whereas the base selectivity
Highly sensitive assay for xanthine oxidase activity by high-performance liquid chromatography with fluorescence detection.
T Sasaoka et al.
Journal of chromatography, 424(2), 392-397 (1988-02-26)