I7388
异黄蝶呤
≥97.5%, powder
别名:
2-氨基-4,7-二羟基-1,3,5,8-四氮杂萘, 2-氨基-4,7-二羟基蝶啶, 2-氨基-4,7-蝶啶二醇
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关于此项目
经验公式（希尔记法）:
C6H5N5O2
化学文摘社编号:
分子量:
179.14
UNSPSC Code:
41106305
NACRES:
NA.51
PubChem Substance ID:
EC Number:
208-469-5
Beilstein/REAXYS Number:
181594
MDL number:
InChI key
GLKCOBIIZKYKFN-UHFFFAOYSA-N
InChI
1S/C6H5N5O2/c7-6-10-4-3(5(13)11-6)8-1-2(12)9-4/h1H,(H4,7,9,10,11,12,13)
SMILES string
NC1=NC2=C(N=CC(=O)N2)C(=O)N1
assay
≥97.5%
form
powder
color
off-white
solubility
1 M NaOH: 50 mg/mL, clear, very dark yellow
storage temp.
room temp
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Application
Isoxanthopterin is a substrate for the enzyme isoxanthopterin deaminase.
Other Notes
Product of xanthine oxidase oxidation of pterin, an enzyme involved in reactive oxygen formation.
存储类别
13 - Non Combustible Solids
wgk
WGK 3
flash_point_f
Not applicable
flash_point_c
Not applicable
ppe
Eyeshields, Gloves, type N95 (US)
Highly sensitive assay for xanthine oxidase activity by high-performance liquid chromatography with fluorescence detection.
T Sasaoka et al.
Journal of chromatography, 424(2), 392-397 (1988-02-26)
S Abadeh et al.
Biochimica et biophysica acta, 1117(1), 25-32 (1992-07-21)
Xanthine oxidase was purified from human milk in yields comparable with those obtained from bovine milk. The freshly purified enzyme appeared homogeneous in gel permeation FPLC and SDS-PAGE, consistent with its being a homodimer with total M(r) 290,000 +/- 6000.
Ciarán A Smyth et al.
Journal of biomedical optics, 16(7), 077007-077007 (2011-08-03)
Optical techniques toward the realization of sensitive and selective biosensing platforms have received considerable attention in recent times. Techniques based on interferometry, surface plasmon resonance, and waveguides have all proved popular, while spectroscopy in particular offers much potential. Raman spectroscopy
Yuichi Komaki et al.
Pulmonary pharmacology & therapeutics, 18(4), 297-302 (2005-03-22)
Reactive oxygen species have been reported to be involved in the airway inflammatory process of chronic obstructive pulmonary disease (COPD). The aim of this study was to quantify the activity of xanthine oxidase (XO), which generates a potent radical superoxide
Burki Rajendar et al.
Bioorganic & medicinal chemistry, 17(1), 351-359 (2008-11-18)
Isoxanthopterin (IX) has two edges with hydrogen bond-forming sites suitable for binding to thymine (T) and cytosine (C). The binding affinity of IX for T or C is stronger than for adenine (A) and guanine (G), whereas the base selectivity
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