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Merck
CN

I7388

Sigma-Aldrich

异黄蝶呤

≥97.5%, powder

别名:

2-氨基-4,7-二羟基-1,3,5,8-四氮杂萘, 2-氨基-4,7-二羟基蝶啶, 2-氨基-4,7-蝶啶二醇

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关于此项目

经验公式(希尔记法):
C6H5N5O2
化学文摘社编号:
分子量:
179.14
Beilstein:
181594
EC 号:
MDL编号:
UNSPSC代码:
41106305
PubChem化学物质编号:
NACRES:
NA.51
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方案

≥97.5%

表单

powder

颜色

off-white

溶解性

1 M NaOH: 50 mg/mL, clear, very dark yellow

储存温度

room temp

SMILES字符串

NC1=NC2=C(N=CC(=O)N2)C(=O)N1

InChI

1S/C6H5N5O2/c7-6-10-4-3(5(13)11-6)8-1-2(12)9-4/h1H,(H4,7,9,10,11,12,13)

InChI key

GLKCOBIIZKYKFN-UHFFFAOYSA-N

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应用

Isoxanthopterin is a substrate for the enzyme isoxanthopterin deaminase.

其他说明

Product of xanthine oxidase oxidation of pterin, an enzyme involved in reactive oxygen formation.

储存分类代码

13 - Non Combustible Solids

WGK

WGK 3

闪点(°F)

Not applicable

闪点(°C)

Not applicable

个人防护装备

Eyeshields, Gloves, type N95 (US)


历史批次信息供参考:

分析证书(COA)

Lot/Batch Number

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R Walter et al.
American journal of respiratory and critical care medicine, 156(6), 2006-2010 (1997-12-31)
Pulmonary endothelial dysfunction is the hallmark of acute lung injury. Impaired pulmonary endothelial nitric oxide (NO) production in this event has been described. Tetrahydrobiopterin (BH4) is an essential cofactor for NO synthase and modulator of its activity. At high local
S Abadeh et al.
Biochimica et biophysica acta, 1117(1), 25-32 (1992-07-21)
Xanthine oxidase was purified from human milk in yields comparable with those obtained from bovine milk. The freshly purified enzyme appeared homogeneous in gel permeation FPLC and SDS-PAGE, consistent with its being a homodimer with total M(r) 290,000 +/- 6000.
Yuichi Komaki et al.
Pulmonary pharmacology & therapeutics, 18(4), 297-302 (2005-03-22)
Reactive oxygen species have been reported to be involved in the airway inflammatory process of chronic obstructive pulmonary disease (COPD). The aim of this study was to quantify the activity of xanthine oxidase (XO), which generates a potent radical superoxide
Ciarán A Smyth et al.
Journal of biomedical optics, 16(7), 077007-077007 (2011-08-03)
Optical techniques toward the realization of sensitive and selective biosensing platforms have received considerable attention in recent times. Techniques based on interferometry, surface plasmon resonance, and waveguides have all proved popular, while spectroscopy in particular offers much potential. Raman spectroscopy
Burki Rajendar et al.
Bioorganic & medicinal chemistry, 17(1), 351-359 (2008-11-18)
Isoxanthopterin (IX) has two edges with hydrogen bond-forming sites suitable for binding to thymine (T) and cytosine (C). The binding affinity of IX for T or C is stronger than for adenine (A) and guanine (G), whereas the base selectivity

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