I7388
异黄蝶呤
≥97.5%, powder
别名:
2-氨基-4,7-二羟基-1,3,5,8-四氮杂萘, 2-氨基-4,7-二羟基蝶啶, 2-氨基-4,7-蝶啶二醇
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关于此项目
经验公式(希尔记法):
C6H5N5O2
化学文摘社编号:
分子量:
179.14
Beilstein:
181594
EC 号:
MDL编号:
UNSPSC代码:
41106305
PubChem化学物质编号:
NACRES:
NA.51
方案
≥97.5%
表单
powder
颜色
off-white
溶解性
1 M NaOH: 50 mg/mL, clear, very dark yellow
储存温度
room temp
SMILES字符串
NC1=NC2=C(N=CC(=O)N2)C(=O)N1
InChI
1S/C6H5N5O2/c7-6-10-4-3(5(13)11-6)8-1-2(12)9-4/h1H,(H4,7,9,10,11,12,13)
InChI key
GLKCOBIIZKYKFN-UHFFFAOYSA-N
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应用
Isoxanthopterin is a substrate for the enzyme isoxanthopterin deaminase.
其他说明
Product of xanthine oxidase oxidation of pterin, an enzyme involved in reactive oxygen formation.
储存分类代码
13 - Non Combustible Solids
WGK
WGK 3
闪点(°F)
Not applicable
闪点(°C)
Not applicable
个人防护装备
Eyeshields, Gloves, type N95 (US)
R Walter et al.
American journal of respiratory and critical care medicine, 156(6), 2006-2010 (1997-12-31)
Pulmonary endothelial dysfunction is the hallmark of acute lung injury. Impaired pulmonary endothelial nitric oxide (NO) production in this event has been described. Tetrahydrobiopterin (BH4) is an essential cofactor for NO synthase and modulator of its activity. At high local
S Abadeh et al.
Biochimica et biophysica acta, 1117(1), 25-32 (1992-07-21)
Xanthine oxidase was purified from human milk in yields comparable with those obtained from bovine milk. The freshly purified enzyme appeared homogeneous in gel permeation FPLC and SDS-PAGE, consistent with its being a homodimer with total M(r) 290,000 +/- 6000.
Yuichi Komaki et al.
Pulmonary pharmacology & therapeutics, 18(4), 297-302 (2005-03-22)
Reactive oxygen species have been reported to be involved in the airway inflammatory process of chronic obstructive pulmonary disease (COPD). The aim of this study was to quantify the activity of xanthine oxidase (XO), which generates a potent radical superoxide
Ciarán A Smyth et al.
Journal of biomedical optics, 16(7), 077007-077007 (2011-08-03)
Optical techniques toward the realization of sensitive and selective biosensing platforms have received considerable attention in recent times. Techniques based on interferometry, surface plasmon resonance, and waveguides have all proved popular, while spectroscopy in particular offers much potential. Raman spectroscopy
Burki Rajendar et al.
Bioorganic & medicinal chemistry, 17(1), 351-359 (2008-11-18)
Isoxanthopterin (IX) has two edges with hydrogen bond-forming sites suitable for binding to thymine (T) and cytosine (C). The binding affinity of IX for T or C is stronger than for adenine (A) and guanine (G), whereas the base selectivity
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