生物来源
rabbit
质量水平
偶联物
unconjugated
抗体形式
affinity isolated antibody
抗体产品类型
primary antibodies
克隆
polyclonal
表单
buffered aqueous solution
分子量
antigen 85 kDa
种属反应性
human
技术
western blot: 0.5 μg/mL using human HeLa cell extract
UniProt登记号
运输
dry ice
储存温度
−20°C
基因信息
human  ...  CHUK(1147)   
一般描述
IKK α is a component of I-κ-B-kinase (IKK) core complex consisting of IKK α, IKK β and IKK γ and belongs to Ser/Thr protein kinase family. It has a pivotal role in NF-κ-B signaling pathway. Anti-IKK α antibody can be used in immunoblot for detecting IKKα (α subunit of IκB kinase). Rabbit anti-IKK α antibody reacts specifically with IKK α (85kD) and has shown no cross reactivity with IKK β or IKK γ.
免疫原
synthetic peptide corresponding to amino acids 716-734 of human IκB Kinase α (IKKα) (C1).
应用
Anti-IKK α antibody can be used in western blotting (diluted 1:1000) using human HeLa cell extract.
外形
Solution in phosphate buffered saline containing 0.02% sodium azide.
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储存分类代码
10 - Combustible liquids
法规信息
新产品
此项目有
J A DiDonato et al.
Nature, 388(6642), 548-554 (1997-08-07)
Nuclear transcription factors of the NF-kappaB/Rel family are inhibited by IkappaB proteins, which inactivate NF-kappaB by trapping it in the cell cytoplasm. Phosphorylation of IkappaBs marks them out for destruction, thereby relieving their inhibitory effect on NF-kappaB. A cytokine-activated protein
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