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K1250

6-Ketocholestanol

Name: 6-Ketocholestanol
Brand: SIGMA

别名:

3β-Hydroxy-5α-cholestan-6-one, 5α-Cholestan-3β-ol-6-one

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关于此项目

经验公式（希尔记法）:

C₂₇H₄₆O₂

化学文摘社编号:

1175-06-0

分子量:

402.65

UNSPSC Code:

12352200

PubChem Substance ID:

24896203

EC Number:

214-640-5

MDL number:

MFCD00003572

Form:

solid

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属性

form

solid

SMILES string

CC(C)CCC[C@@H](C)[C@H]1CC[C@H]2[C@@H]3CC(=O)[C@H]4C[C@@H](O)CC[C@]4(C)[C@H]3CC[C@]12C

InChI

1S/C27H46O2/c1-17(2)7-6-8-18(3)21-9-10-22-20-16-25(29)24-15-19(28)11-13-27(24,5)23(20)12-14-26(21,22)4/h17-24,28H,6-16H2,1-5H3/t18-,19+,20+,21-,22+,23+,24-,26-,27-/m1/s1

InChI key

JQMQKOQOLPGBBE-ZNCJEFCDSA-N

说明

存储类别

13 - Non Combustible Solids

wgk

WGK 3

flash_point_f

Not applicable

flash_point_c

Not applicable

ppe

Eyeshields, Gloves, type N95 (US)

法规信息

新产品

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历史批次信息供参考:

分析证书(COA)

Lot/Batch Number

069H1195

129F0459

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Phloretin and 6-ketocholestanol: membrane interactions studied by a phospholipid/polydiacetylene colorimetric assay and differential scanning calorimetry.

C Valenta et al.

European journal of pharmaceutics and biopharmaceutics : official journal of Arbeitsgemeinschaft fur Pharmazeutische Verfahrenstechnik e.V, 57(2), 329-336 (2004-03-17)

The aim of this study was to investigate membrane interactions of phloretin and 6-ketocholestanol using different methods. A previously reported colorimetric assay with phospholipid/polydiacetylene (PDA) vesicles was used to examine a possible interaction of phloretin and 6-ketocholestanol with this target.

Control of a redox reaction on lipid bilayer surfaces by membrane dipole potential.

J I Alakoskela et al.

Biophysical journal, 80(1), 294-304 (2001-02-13)

Nitro-2,1,3-benzoxadiazol-4-yl (NBD) group is a widely used, environment-sensitive fluorescent probe. The negatively charged dithionite rapidly reduces the accessible NBD-labeled lipids in liposomes to their corresponding nonfluorescent derivatives. In this study both the phospholipid headgroup and acyl chain NBD-labeled L-alpha-1,2-dipalmitoyl-sn-glycero-3-phospho-[N-(4-nitrobenz-2-oxa-1,3-diazole)-ethanolamine] (DPPN)

Phlorizin- and 6-ketocholestanol-mediated antagonistic modulation of alamethicin activity in phospholipid planar membranes.

Tudor Luchian et al.

Langmuir : the ACS journal of surfaces and colloids, 22(20), 8452-8457 (2006-09-20)

As a result of the interfacial chemical heterogenity, membrane-penetrating peptides will experience a dramatic variation in environmental polarity manifested via electrical interactions with the surface and dipole potential of membranes prone to modulate the membrane insertion and folding of different

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全球贸易项目编号

货号	GTIN
K1250-1G	04061826236703