K1513
Kendomycin from Streptomyces violaceoruber
solid
别名:
(−)-TAN 2162
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关于此项目
经验公式(希尔记法):
C29H42O6
化学文摘社编号:
分子量:
486.64
MDL编号:
UNSPSC代码:
12352202
PubChem化学物质编号:
NACRES:
NA.77
表单
solid
质量水平
抗生素抗菌谱
Gram-negative bacteria
Gram-positive bacteria
neoplastics
作用机制
protein synthesis | interferes
储存温度
−20°C
SMILES字符串
CC(C)CC(N)C(=O)NC(CCCNC(N)=N)C(=O)NC(CCCNC(N)=N)C(=O)NC(C)C(=O)NC(CO)C(=O)NC(C(C)C)C(=O)NC(C)C(O)=O
InChI
1S/C32H61N13O9/c1-15(2)13-19(33)25(48)42-21(10-8-12-39-32(36)37)27(50)43-20(9-7-11-38-31(34)35)26(49)40-17(5)24(47)44-22(14-46)28(51)45-23(16(3)4)29(52)41-18(6)30(53)54/h15-23,46H,7-14,33H2,1-6H3,(H,40,49)(H,41,52)(H,42,48)(H,43,50)(H,44,47)(H,45,51)(H,53,54)(H4,34,35,38)(H4,36,37,39)
InChI key
PPBZOEOSJVJLRX-UHFFFAOYSA-N
一般描述
Chemical structure: peptide
生化/生理作用
Potent endothelin receptor antagonist. Antiosteoporotic compound. Shows also remarkable antibacterial and cytotoxic activity. A putative cellular target for cytotoxicity has been identified: inhibition or altered regulation of the proteasome.
储存分类代码
11 - Combustible Solids
WGK
WGK 3
闪点(°F)
Not applicable
闪点(°C)
Not applicable
个人防护装备
Eyeshields, Gloves, type N95 (US)
法规信息
新产品
此项目有
Structure and biosynthesis of kendomycin, a carboxylic ansa-compound from Streptomyces. .
Zeeck, A. , and Bode, H.B.
Journal of the Chemical Society. Perkin Transactions 1, 323-323 (2000)
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