L0130
β-乳球蛋白 来源于牛奶
≥90% (PAGE), lyophilized powder
别名:
β-LG, Bos d 5, beta-LG
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关于此项目
Form:
lyophilized powder
Assay:
≥90% (PAGE)
Biological source:
bovine milk
biological source
bovine milk
Quality Level
assay
≥90% (PAGE)
form
lyophilized powder
UniProt accession no.
storage temp.
2-8°C
Gene Information
bovine ... LGB(280838)
General description
作为脂质运载蛋白家族的成员，β-乳球蛋白（βLg）是162个氨基酸的小蛋白质，分子量为∼18,400Da。它具有八链β-桶（链A-H），其后面是三转α-螺旋和最终 β-链（链I），其形成二聚化界面的一部分。
来自奶牛的牛奶含有蛋白质 β-乳球蛋白（BLG）。它天然存在于许多遗传变异体中，最普遍的牛变体是BLG A和BLG B。
Application
来自牛奶的β-乳球蛋白用于测试对牛′s 奶过敏的儿童过敏原反应性 CD4 + CD25 + 调节性 T细胞。它还用于测试 Tween 20 从油 - 水和空气 - 水界面的β-乳球蛋白的竞争性置换。
Preparation Note
结晶
Analysis Note
可能不含叶酸结合蛋白；不推荐用于叶酸分析。
Other Notes
含 β-乳球蛋白 A 和 B，可通过色谱法分离。
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存储类别
11 - Combustible Solids
wgk
WGK 3
flash_point_f
Not applicable
flash_point_c
Not applicable
ppe
Eyeshields, Gloves, type N95 (US)
法规信息
低风险生物材料
此项目有
Isabella Pali-Schöll et al.
Clinical and translational allergy, 12(2), e12125-e12125 (2022-02-17)
Growing up on a cattle farm and consuming raw cow's milk protects against asthma and allergies. We expect a cattle-specific protein as active component in this farm effect. Dust was collected from cattle and poultry stables and from mattresses of
A Heinzmann et al.
International archives of allergy and immunology, 120(4), 280-286 (2000-01-21)
beta-Lactoglobulin (BLG) represents one of the major allergens causing cow's milk allergy (CMA) - a disease with a wide spectrum of clinical symptoms. The aim of this study was to evaluate sequential B cell epitopes of BLG by the Pin-ELISA
Nicholas A Smith et al.
Brain, behavior, and immunity, 95, 122-141 (2021-03-12)
A number of studies have reported comorbidity of food allergies with various neuropsychiatric disorders, such as anxiety, depression, attention-deficit hyperactivity disorder, and autism. However, inconsistent results across clinical studies have left the association between food allergy and behavioral disorders inconclusive.
全球贸易项目编号
| 货号 | GTIN |
|---|---|
| L0130-1G | 04061833945575 |
| L0130-5G | 04061833945582 |