L1626
亚油酸
~60%
别名:
顺-9,顺-12-十八碳二烯酸
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线性分子式:
CH3(CH2)4CH=CHCH2CH=CH(CH2)7CO2H
化学文摘社编号:
分子量:
280.45
EC Number:
200-470-9
UNSPSC Code:
12352211
MDL number:
Beilstein/REAXYS Number:
1727101
InChI key
OYHQOLUKZRVURQ-HZJYTTRNSA-N
InChI
1S/C18H32O2/c1-2-3-4-5-6-7-8-9-10-11-12-13-14-15-16-17-18(19)20/h6-7,9-10H,2-5,8,11-17H2,1H3,(H,19,20)/b7-6-,10-9-
SMILES string
OC(CCCCCCC/C=C\C/C=C\CCCCC)=O
concentration
~60%
bp
229-230 °C/16 mmHg (lit.)
mp
−5 °C (lit.)
density
0.902 g/mL at 25 °C (lit.)
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Biochem/physiol Actions
在原代鸭肝细胞中，亚油酸可增加PPARα及其靶基因（如酰基辅酶A氧化酶）的细胞增殖和基因表达 。
存储类别
10 - Combustible liquids
wgk
WGK 1
flash_point_f
>235.4 °F - closed cup
flash_point_c
> 113 °C - closed cup
ppe
Eyeshields, Gloves, multi-purpose combination respirator cartridge (US)
法规信息
新产品
此项目有
F Valianpour et al.
Journal of lipid research, 44(3), 560-566 (2003-02-04)
The object of this study was to investigate whether the levels of cardiolipin in cultured skin fibroblasts of patients with Barth syndrome (BTHS) can be restored by addition of linoleic acid to growth media. To this end, fibroblasts from controls
Antonius H M Terpstra
The American journal of clinical nutrition, 79(3), 352-361 (2004-02-27)
Studies in mice have indicated that feeding diets containing 0.5-1% conjugated linoleic acid (CLA) considerably reduces body fat. These findings have attracted much interest because of the potential use of CLA as a tool to promote weight loss in humans.
Robert A Gibson et al.
Maternal & child nutrition, 7 Suppl 2, 17-26 (2011-03-05)
Over the past two decades, there has been a marked shift in the fatty acid composition of the diets of industrialized nations towards increased intake of the n-6 fatty acid linoleic acid (LA, 18:2n-6), largely as a result of the
Leanne Hodson et al.
The Journal of nutrition, 144(1), 33-41 (2013-11-15)
Erythrocytes, compared with plasma, are considered more robust markers of n-3 (ω-3) polyunsaturated fatty acid (PUFA) intake, because dietary-induced change in fatty acid (FA) composition takes longer to complete. The extent to which this applies to intakes of saturated fatty
Christopher E Ramsden et al.
BMJ (Clinical research ed.), 346, e8707-e8707 (2013-02-07)
To evaluate the effectiveness of replacing dietary saturated fat with omega 6 linoleic acid, for the secondary prevention of coronary heart disease and death. Evaluation of recovered data from the Sydney Diet Heart Study, a single blinded, parallel group, randomized
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