重组
expressed in E. coli
方案
>98% (HPLC)
表单
lyophilized powder
分子量
4359 Da
储存温度
−20°C
Amino Acid Sequence
Gln-Phe-Thr-Gln-Glu-Ser-Cys-Thr-Ala-Ser-Asn-Gln-Cys-Trp-Ser-Ile-Cys-Lys-Arg-Leu-His-Asn-Thr-Asn-Arg-Gly-Lys-Cys-Met-Asn-Lys-Lys-Cys-Arg-Cys-Tyr-Ser
生化/生理作用
ROMK1 inward rectifier potassium channel blocker; also blocks single K(Ca) channels in planar lipid bilayer (rat muscle); Lq2 action is on the extracellular side of the pore.
储存分类代码
13 - Non Combustible Solids
WGK
WGK 3
闪点(°F)
Not applicable
闪点(°C)
Not applicable
个人防护装备
Eyeshields, Gloves, type N95 (US)
法规信息
新产品
此项目有
Z Lu et al.
Biochemistry, 36(23), 6936-6940 (1997-06-10)
We have purified a protein inhibitor of an inward-rectifier K+ channel, ROMK1, from the venom of the scorpion Leiurus quinquestriatus var. hebraeus. The inhibitor is Lq2, a previously discovered blocker of voltage- and Ca2+-activated K+ channels. Mutations were made on
K Lucchesi et al.
The Journal of membrane biology, 109(3), 269-281 (1989-08-01)
Two charybdotoxin peptides were purified from venom of the Israeli scorpion, Leiurus quinquestriatus hebraeus. Microsequencing of the most abundant toxin, ChTX-Lq1, revealed identity with the 37-residue peptide previously sequenced by Gimenez-Gallego et al. [Gimenez-Gallego, G., et al., Proc. Natl. Acad.
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