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Merck
CN

L2917

Anti-phospho-Lck (pSer158) antibody produced in rabbit

affinity isolated antibody, buffered aqueous solution

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UNSPSC Code:
12352203
MDL number:
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antibody form

affinity isolated antibody

clone

polyclonal

form

buffered aqueous solution

species reactivity

human

technique(s)

western blot: 0.1-1.0 μg/mL using full length recombinant human Lck protein.

shipped in

dry ice

storage temp.

−70°C

Gene Information

human ... LCK(3932)
mouse ... Lck(16818)

Immunogen

synthetic phosphopeptide derived from the region of Lck that is phosphorylated on serine 158. Mouse and human have 100% homology.

Physical form

Solution in phosphate buffer, pH 7.4, containing 1 mg/mL BSA (IgG and protease free) and 0.05% sodium azide.

Preparation Note

The antibody is preadsorbed to remove any reactivity towards a non-phosphorylated Lck.


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W Fujimaki et al.
The Journal of biological chemistry, 276(20), 17455-17460 (2001-03-30)
Human thymic CD1a-CD4+ T cells in the final stage of thymic maturation are susceptible to anergy induced by a superantigen, toxic shock syndrome toxin-1 (TSST-1). Thymic CD4+ T-cell blasts, established by stimulating human thymic CD1a-CD4+ T cells with TSST-1 in