L3040

L-765,314 hydrate

Name: L-765,314 hydrate
Brand: SIGMA

≥98% (HPLC), solid

别名:

(2S)-4-(4-amino-6,7-dimethoxy-2-quinazolinyl)-2-[[(1,1-dimethylethyl)amino]carbonyl]-1-piperazinecarboxylic acid, phenylmethyl ester hydrate

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关于此项目

经验公式（希尔记法）:

C₂₇H₃₄N₆O₅ · xH₂O

分子量:

522.60 (anhydrous basis)

MDL编号:

MFCD11045931

UNSPSC代码:

12352200

PubChem化学物质编号:

24278734

主要文件

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方案

≥98% (HPLC)

表单

solid

溶解性

DMSO: 14 mg/mL

创始人

Merck & Co., Inc., Kenilworth, NJ, U.S.

SMILES字符串

O.COc1cc2nc(nc(N)c2cc1OC)N3CCN([C@@H](C3)C(=O)NC(C)(C)C)C(=O)OCc4ccccc4

InChI

1S/C27H34N6O5.H2O/c1-27(2,3)31-24(34)20-15-32(11-12-33(20)26(35)38-16-17-9-7-6-8-10-17)25-29-19-14-22(37-5)21(36-4)13-18(19)23(28)30-25;/h6-10,13-14,20H,11-12,15-16H2,1-5H3,(H,31,34)(H2,28,29,30);1H2/t20-;/m0./s1

InChI key

KQHMFDHSRXAELV-BDQAORGHSA-N

基因信息

human ... ADRA1A(148), ADRA1B(147), ADRA1D(146)
rat ... Adra1a(29412), Adra1b(24173), Adra1d(29413)

生化/生理作用

Potent and selective α_1B-adrenoceptor antagonist.

特点和优势

This compound is featured on the α1-Adrenoceptors page of the Handbook of Receptor Classification and Signal Transduction. To browse other handbook pages, click here.

This compound was developed by Merck & Co., Inc., Kenilworth, NJ, U.S.. To browse the list of other pharma-developed compounds and Approved Drugs/Drug Candidates, click here.