L3776
Leukotriene C3
~50 μg/mL in methanol: water (7:3) containing 17 mM acetate buffer adjusted to pH 5.4 with NH4OH, ≥97% (HPLC)
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关于此项目
经验公式（希尔记法）:
C30H49N3O9S
化学文摘社编号:
分子量:
627.79
UNSPSC Code:
12352211
PubChem Substance ID:
MDL number:
assay
≥97% (HPLC)
concentration
~50 μg/mL in methanol: water (7:3) containing 17 mM acetate buffer adjusted to pH 5.4 with NH4OH
functional group
carboxylic acid
shipped in
dry ice
storage temp.
−20°C
SMILES string
CCCCCCCC\C=C\C=C\C=C\C(SCC(NC(=O)CCC(N)C(O)=O)C(=O)NCC(O)=O)C(O)CCCC(O)=O
InChI
1S/C30H49N3O9S/c1-2-3-4-5-6-7-8-9-10-11-12-13-16-25(24(34)15-14-17-27(36)37)43-21-23(29(40)32-20-28(38)39)33-26(35)19-18-22(31)30(41)42/h9-13,16,22-25,34H,2-8,14-15,17-21,31H2,1H3,(H,32,40)(H,33,35)(H,36,37)(H,38,39)(H,41,42)/b10-9+,12-11+,16-13+
InChI key
AIJDQMYBRDJHHT-FNBQXVLZSA-N
Packaging
Packaged under argon.
存储类别
10 - Combustible liquids
wgk
WGK 3
flash_point_f
Not applicable
flash_point_c
Not applicable
ppe
Eyeshields, Faceshields, Gloves, type ABEK (EN14387) respirator filter
法规信息
危险化学品
此项目有
E J Li et al.
Circulatory shock, 31(2), 159-170 (1990-06-01)
Resistance to endotoxin in essential fatty acid-deficient (EFAD) rats is associated with reduced synthesis of certain arachidonic acid metabolites. It was hypothesized that EFAD rats would manifest decreased vascular permeability changes during endotoxemia as a consequence of reduced arachidonic acid
S Hammarström et al.
Advances in prostaglandin, thromboxane, and leukotriene research, 16, 383-396 (1986-01-01)
In vitro and in vivo experiments have demonstrated that a major pathway of metabolism of the glutathione containing leukotrienes involves modifications of the tripeptide substituent. The metabolic alterations are initiated by elimination of the N-terminal gamma-glutamyl residue, catalyzed by the
S Hammarström
The Journal of biological chemistry, 256(18), 9573-9578 (1981-09-25)
[5,6,8,9,11,12-3H6]Leukotriene C3 was converted to polar metabolites which ere excreted in feces and urine for 4-5 days after subcutaneous administration to guinea pigs. Lung homogenates converted leukotriene C3 to leukotriene D3. Liver and kidney homogenates did not catabolize leukotriene C3
Metabolism of leukotriene C3.
S Hammarström
Advances in prostaglandin, thromboxane, and leukotriene research, 9, 83-101 (1982-01-01)
S E Dahlén et al.
European journal of pharmacology, 86(2), 207-215 (1982-12-24)
Eight biosynthetically formed cysteine-containing leukotrienes dose dependently (0.01-100 nM) contracted parenchymal strips of guinea-pig lung. The response to the leukotrienes was slow in onset, remarkably long-lasting and often tachyphylactic upon repeated administration. All the leukotrienes (LTC3, 8,9-LTC3, LTC4, 11-trans-LTC4, LTC5
相关内容
Datasheet
全球贸易项目编号
| 货号 | GTIN |
|---|---|
| L3776-10UG | 04061837122262 |
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