L5152
Lewis-X trisaccharide
≥99% (HPLC)
别名:
α-L-Fuc-(1→3)-[β-D-Gal-(1→4)]-D-GlcNAc, Lex Trisaccharide
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关于此项目
经验公式（希尔记法）:
C20H35NO15
化学文摘社编号:
分子量:
529.49
UNSPSC Code:
12352200
PubChem Substance ID:
MDL number:
InChI
1S/C20H35NO15/c1-6-11(27)13(29)15(31)19(33-6)35-17(8(3-22)21-7(2)25)18(9(26)4-23)36-20-16(32)14(30)12(28)10(5-24)34-20/h3,6,8-20,23-24,26-32H,4-5H2,1-2H3,(H,21,25)
SMILES string
CC1OC(OC(C(NC(C)=O)C=O)C(OC2OC(CO)C(O)C(O)C2O)C(O)CO)C(O)C(O)C1O
InChI key
ZAFUNKXZZPSTLA-UHFFFAOYSA-N
assay
≥99% (HPLC)
storage temp.
2-8°C
Biochem/physiol Actions
Lewis-X is a developmentally regulated antigen and has been suggested to be a tumor marker. At high concentrations, it inhibits P-selectin−mediated adhesion.
Other Notes
Lewis-X is the trisaccharide part of the sialyl-Lewis-X tetrasaccharide, the suggested ligand for P- and E-selectins.
法规信息
新产品
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L A Lasky
Science (New York, N.Y.), 258(5084), 964-969 (1992-11-06)
Although a bewildering array of cell surface carbohydrate structures have been described, the physiological relevance of any of these complex molecules has often eluded biologists. A family of cell surface glycoproteins, the "selectins," has a characteristic ability to use some
Wilkins, W.M., et al.
ACS Symp. Ser., 519, 34-34 (1993)
Marko Haramija et al.
Rapid communications in mass spectrometry : RCM, 31(20), 1709-1719 (2017-08-15)
Affinity mass spectrometry (AMS) is an emerging tool in the field of the study of protein•carbohydrate complexes. However, experimental obstacles and data analysis are preventing faster integration of AMS methods into the glycoscience field. Here we show how analysis of
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