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Merck
CN

L6792

Anti-Luteinizing Hormone/Choriogonadotropin Receptor antibody produced in rabbit

affinity isolated antibody, buffered aqueous solution

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UNSPSC Code:
12352203
MDL number:
Conjugate:
unconjugated
Clone:
polyclonal
Application:
IHC (p)
Citations:
3
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biological source

rabbit

conjugate

unconjugated

antibody form

affinity isolated antibody

antibody product type

primary antibodies

clone

polyclonal

form

buffered aqueous solution

species reactivity

human

concentration

~1 mg/mL

technique(s)

immunohistochemistry (formalin-fixed, paraffin-embedded sections): 1-6 μg/mL using human ovary, corpus luteum.

UniProt accession no.

shipped in

dry ice

storage temp.

−20°C

target post-translational modification

unmodified

Gene Information

human ... LHCGR(3973)
mouse ... Lhcgr(16867)
rat ... Lhcgr(25477)

Immunogen

synthetic peptide corresponding to the N-terminal extracellular domain of human luteinizing hormone/choriogonadotropin receptor, conjugated to KLH. The immunizing peptide has 84% similarity with the mouse.

Biochem/physiol Actions

Luteinizing hormone (LH) is produced by the pituitary gland on stimulation gonadotrophin-releasing hormone secreted by the hypothalamus. LH binds to the LH receptor present on the Leydig cells of testis to stimulate the production of testosterone. In ovary, LH controls the ovulation, maturation of oocytes and gonadal steroidogenesis.

Physical form

Solution in phosphate buffered saline, 0.1% sodium azide.

Disclaimer

Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.

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存储类别

12 - Non Combustible Liquids

wgk

nwg

flash_point_f

Not applicable

flash_point_c

Not applicable

法规信息

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分析证书(COA)

Lot/Batch Number

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S Whirledge et al.
Minerva endocrinologica, 35(2), 109-125 (2010-07-03)
Modifications of the hypothalamo-pituitary-adrenal axis and associated changes in circulating levels of glucocorticoids form a key component of the response of an organism to stressful challenges. Increased levels of glucocorticoids promote gluconeogenesis, mobilization of amino acids, and stimulation of fat
Xiaoyan Pan et al.
Experimental and therapeutic medicine, 15(1), 813-821 (2018-02-06)
The aim of the present study was to investigate the potential protective effects of new Wenshen Shengjing Decoction (new WSSJD; including Cornu Cervi Nippon Parvum, Panax ginseng, Cynomorium songaricum, Cistanche deserticola, Radix Astragali, Epimedium brevicornum and Angelica sinensis) on cyclosporine-induced
David Puett et al.
Molecular and cellular endocrinology, 329(1-2), 47-55 (2010-05-07)
The luteinizing hormone receptor (LHR), one of the three glycoprotein hormone receptors, is necessary for critical reproductive processes, including gonadal steroidogenesis, oocyte maturation and ovulation, and male sex differentiation. Moreover, it has been postulated to contribute to certain neoplasms, particularly

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