form
lyophilized powder
potency
<10 μg per mL agglutination activity
composition
Protein, ≥85% Lowry
impurities
salt, essentially free
storage temp.
2-8°C
Biochem/physiol Actions
MAA由两种分子组成，一种是强血凝性血凝素（MAH），一种是强促有丝分裂性血凝素（MAL）。后者的有丝分裂活性可被α-唾液酸基-[2→3]-乳糖抑制。MAA可与含唾液酸的糖缀合物相互作用，可用于分级分离唾液酸化的寡糖。
Preparation Note
通过亲和色谱法，使用改进的Wang和Cummings方法进行纯化。
Analysis Note
凝集活性以 μg/ml表示，并且是基于1mg/ml磷酸盐缓冲盐水（pH 7.2）的系列稀释液进行测定的。该活性是在25℃条件下温育1小时后凝集2％人血型O红细胞悬浮液的最低浓度。
存储类别
11 - Combustible Solids
wgk
WGK 3
flash_point_f
Not applicable
flash_point_c
Not applicable
ppe
Eyeshields, Gloves, type N95 (US)
法规信息
常规特殊物品
此项目有
W C Wang et al.
The Journal of biological chemistry, 263(10), 4576-4585 (1988-04-05)
We recently reported that the purified leukoagglutinin (designated MAL) from the seeds of the leguminous plant Maackia amurensis is a potent leukoagglutinin for the mouse lymphoma cell line BW5147 (Wang, W.-C., and Cummings, R. D. (1987) Anal. Biochem. 161,80). We
Jhon Alberto Ochoa-Alvarez et al.
PloS one, 7(7), e41845-e41845 (2012-07-31)
Cancer is a leading cause of death of men and women worldwide. Tumor cell motility contributes to metastatic invasion that causes the vast majority of cancer deaths. Extracellular receptors modified by α2,3-sialic acids that promote this motility can serve as
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