表单
lyophilized powder
效能
<10 μg per mL agglutination activity
组成
Protein, ≥85% Lowry
杂质
salt, essentially free
储存温度
2-8°C
生化/生理作用
MAA由两种分子组成,一种是强血凝性血凝素(MAH),一种是强促有丝分裂性血凝素(MAL)。后者的有丝分裂活性可被α-唾液酸基-[2→3]-乳糖抑制。MAA可与含唾液酸的糖缀合物相互作用,可用于分级分离唾液酸化的寡糖。
制备说明
通过亲和色谱法,使用改进的Wang和Cummings方法进行纯化。
分析说明
凝集活性以 μg/ml表示,并且是基于1mg/ml磷酸盐缓冲盐水(pH 7.2)的系列稀释液进行测定的。该活性是在25℃条件下温育1小时后凝集2%人血型O红细胞悬浮液的最低浓度。
储存分类代码
11 - Combustible Solids
WGK
WGK 3
闪点(°F)
Not applicable
闪点(°C)
Not applicable
个人防护装备
Eyeshields, Gloves, type N95 (US)
法规信息
常规特殊物品
此项目有
W C Wang et al.
The Journal of biological chemistry, 263(10), 4576-4585 (1988-04-05)
We recently reported that the purified leukoagglutinin (designated MAL) from the seeds of the leguminous plant Maackia amurensis is a potent leukoagglutinin for the mouse lymphoma cell line BW5147 (Wang, W.-C., and Cummings, R. D. (1987) Anal. Biochem. 161,80). We
Jhon Alberto Ochoa-Alvarez et al.
PloS one, 7(7), e41845-e41845 (2012-07-31)
Cancer is a leading cause of death of men and women worldwide. Tumor cell motility contributes to metastatic invasion that causes the vast majority of cancer deaths. Extracellular receptors modified by α2,3-sialic acids that promote this motility can serve as
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