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Merck
CN

L8141

Sigma-Aldrich

Anti-Human Lambda Light Chain (Bound and Free) antibody produced in rabbit

whole antiserum

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关于此项目

MDL编号:
UNSPSC代码:
12352203
NACRES:
NA.46
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生物来源

rabbit

偶联物

unconjugated

抗体形式

whole antiserum

抗体产品类型

secondary antibodies

克隆

polyclonal

包含

15 mM sodium azide

技术

quantitative precipitin assay: 1.5

运输

dry ice

储存温度

−20°C

靶向翻译后修饰

unmodified

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一般描述

Lambda (λ) light chain has an amino-terminal variable region and carboxy-terminal constant region. λ chain is biologically important and constitutes 30 to 40% of human immunoglobulin (Ig) molecules. The human λ locus is mapped to human chromosome 22.

生化/生理作用

Immunoglobulins (Ig) are produced by the B cells and play crucial role in host humoral immune response. A typical immunoglobulin consists of two heavy chains and two light chains. The two light chains are either κ or the λ chain. The B cells express one type of light chain during their life time.

免责声明

Unless otherwise stated in our catalog, our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.

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储存分类代码

12 - Non Combustible Liquids

WGK

nwg

闪点(°F)

Not applicable

闪点(°C)

Not applicable

法规信息

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分析证书(COA)

Lot/Batch Number

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B-cell development
Hematology (2018)
Structural and functional properties of human lambda-light-chain variable-region subgroups.
A Solomon et al.
Clinical and diagnostic laboratory immunology, 2(4), 387-394 (1995-07-01)
Jerry A Katzmann et al.
Clinical chemistry, 48(9), 1437-1444 (2002-08-27)
The detection of monoclonal free light chains (FLCs) is an important diagnostic aid for a variety of monoclonal gammopathies and is especially important in light-chain diseases, such as light-chain myeloma, primary systemic amyloidosis, and light-chain-deposition disease. These diseases are more

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