biological source
Salmonella enterica (Serotype minnesota Re 595 mutant)
form
lyophilized powder
impurities
<3% Protein (Lowry)
color
white to yellow cast
solubility
water: 0.90-1.10 mg/mL, hazy to turbid, colorless to faintly yellow
shipped in
ambient
storage temp.
2-8°C
Quality Level
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Application
- 电荷和聚集模式决定了塑化素与模拟革兰氏阴性菌外膜外叶的LPS单层的相互作用：该研究探讨了电荷和聚集模式如何影响塑化素与来自肠道沙门氏菌血清型Minnesota Re 595等粗糙菌株的脂多糖（LPS）相互作用。这些发现有助于理解微生物耐药机制中涉及的分子相互作用（Michel et al., 2015）。
Biochem/physiol Actions
脂多糖（LPS）位于膜的外层，并且在非包封的菌株中，其暴露于细胞表面。它们有助于外膜的完整性，并可保护细胞免受胆汁盐和亲脂性抗生素的作用。
General description
本品由沙门氏菌菌种明尼苏达粒径Re 595（Re突变体）采用酚-氯仿-石油醚提取程序制备而成。来源菌株为 ATCC 49284。菌株 Re 595 的 LPS 中的一种独特结构显示可诱导人血小板分泌和聚集。
Preparation Note
通过苯酚-氯仿-石油醚萃取进行制备。
本品可溶于水（5 mg/ml）或细胞培养基（1 mg/ml），产生混浊的淡黄色溶液。溶于生理盐水并涡旋和加热至70-80 oC后，可形成浓度更高但仍然混浊的溶液（20 mg/ml）。脂多糖分子可在各种溶剂中形成胶束。溶于水和磷酸盐缓冲盐水时，可观察到浑浊的溶液。使用有机溶剂不能形成更清晰的溶液。使用甲醇可产生具有漂浮物的混浊悬浮液，而溶于水会产生均匀的混浊溶液。
本品可溶于水（5 mg/ml）或细胞培养基（1 mg/ml），产生混浊的淡黄色溶液。溶于生理盐水并涡旋和加热至70-80 oC后，可形成浓度更高但仍然混浊的溶液（20 mg/ml）。脂多糖分子可在各种溶剂中形成胶束。溶于水和磷酸盐缓冲盐水时，可观察到浑浊的溶液。使用有机溶剂不能形成更清晰的溶液。使用甲醇可产生具有漂浮物的混浊悬浮液，而溶于水会产生均匀的混浊溶液。
signalword
Warning
hcodes
pcodes
Hazard Classifications
Acute Tox. 4 Oral
存储类别
11 - Combustible Solids
wgk
WGK 3
flash_point_f
Not applicable
flash_point_c
Not applicable
ppe
dust mask type N95 (US), Eyeshields, Gloves
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