M1552
Matrix Metalloproteinase-9 from mouse
recombinant, expressed in NSO cells, buffered aqueous solution
别名:
105 kDa Gelatinase, Gelatinase-B, MMP-9
recombinant
expressed in NSO cells
form
buffered aqueous solution
UniProt accession no.
shipped in
dry ice
storage temp.
−70°C
Gene Information
mouse ... Mmp9(17395)
Biochem/physiol Actions
MMP-9 degrades the collagens, which make up the extracellular matrix; role in the control of angiogenesis.
Physical form
Solution in 50 mM Tris-HCl, 10 mM calcium chloride, 150 mM sodium chloride, and 0.05% Brij 35.
Analysis Note
The specific activity is measured by its ability to cleave a fluorescent peptide substrate and measured by excitation and emission wavelengths.
存储类别
12 - Non Combustible Liquids
wgk
WGK 1
flash_point_f
Not applicable
flash_point_c
Not applicable
ppe
Eyeshields, Gloves, multi-purpose combination respirator cartridge (US)
法规信息
新产品
此项目有
M S Hibbs et al.
The Journal of clinical investigation, 80(6), 1644-1650 (1987-12-01)
Human pulmonary alveolar macrophages obtained by bronchoalveolar lavage from both normal controls and smokers secreted in vitro a neutral proteinase that degraded denatured collagens. Optimal expression of the proteinase was detected after 3-5 d of culture. The proteinase could not
T H Vu et al.
Cell, 93(3), 411-422 (1998-05-20)
Homozygous mice with a null mutation in the MMP-9/gelatinase B gene exhibit an abnormal pattern of skeletal growth plate vascularization and ossification. Although hypertrophic chondrocytes develop normally, apoptosis, vascularization, and ossification are delayed, resulting in progressive lengthening of the growth
Marzena Schiwon et al.
Cell, 156(3), 456-468 (2014-02-04)
The phagocytes of the innate immune system, macrophages and neutrophils, contribute to antibacterial defense, but their functional specialization and cooperation is unclear. Here, we report that three distinct phagocyte subsets play highly coordinated roles in bacterial urinary tract infection. Ly6C(-)
M Florencia Iulita et al.
Brain : a journal of neurology, 137(Pt 3), 860-872 (2014-02-13)
Basal forebrain cholinergic neurons play a key role in cognition. This neuronal system is highly dependent on NGF for its synaptic integrity and the phenotypic maintenance of its cell bodies. Basal forebrain cholinergic neurons progressively degenerate in Alzheimer's disease and
Matrix metalloproteinases 2 and 9 as diagnostic markers in the progression to Chagas cardiomyopathy.
Norma Leticia Bautista-López et al.
American heart journal, 165(4), 558-566 (2013-03-30)
Infection with the Trypanosoma cruzi parasite is endemic in parts of Central and South America. Approximately 30% of those infected develop Chagas cardiomyopathy, the most common cause of heart failure in this region. No suitable biomarker is available that reflects
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